Category: Biotherapeutic Index

Injection solution Composition:

Injection solution: 1.1 ml cont.: Chelidonium majus D10, Chelidonium majus D30, Chelidonium majus D200, Atropa belladonna D10, Atropa belladonna D30, Atropa belladonna D200, Atropa belladonna D1000 2.2 µl each; Carduus marianus D10, Carduus marianus D30, Carduus marianus D200, China D10, China D30, China D200, Calcium carbonicum Hahnemanni D10, Calcium carbonicum Hahnemanni D30, Calcium carbonicum Hahnemanni D200, Lycopodium clavatum D10, Lycopodium clavatum D30, Lycopodium clavatum D200, Lycopodium clavatum D1000, Taraxacum officinale D10, Taraxacum officinale D30, Taraxacum officinale D200, Veratrum album D10, Veratrum album D30, Veratrum album D200 1.1 µl each.

Indications:

Cholangitis, cholecystitis, cholelithiasis; dysfunction of the liver, chronic hepatitis.

Dosage:

In acute disorders daily, otherwise 3-1 times weekly 1 ampoule i.m., s.c., i.d., i.v. Package sizes:

Packs containing 5, 10, 50 and 100 ampoules of 1.1 ml.

Pharmacological and clinical notes

Chelidonium majus (celandine)

Cholelithiasis, cholecystitis, cholangitis, biliary colic, pains under the right shoulder blade, hepatopathy.

Atropa belladonna (deadly nightshade)

Biliary colic (necessitating stretching out straight), vomiting. Carduus marianus (milk thistle)

Liver damage, congestion of the portal vein, biliary colic, cholangitis, cholecystitis, cholelithiasis.

China (Peruvian bark)

Remedy for debility, flatulent colic, biliary colic, enlargement of liver, gastroduodenitis. Calcium carbonicum Hahnemanni (inner white portion of the oyster shell)

Conditions of exhaustion, pain in the epigastrium upon contact, flatulence (firmly established), biliary colic.

Lycopodium clavatum (club-moss)

Diseases of the liver, gall bladder and bile duct, loss of appetite or Iycorexia, meteorism, sallow complexion.

Taraxacum officinale (dandelion)

Cholecystopathy, hepatopathy with and without jaundice, meteorism, flatulence, congestion of the portal vein, gastritis.

Veratrum album (white hellebore)

Affections starting feverishly, chronic vomiting, diarrhoea, conditions of collapse.  Based on the individual homoeopathic constituents of Injeel-Chol, therapeutical possibilities result for the treatment of functional disorders of the liver, damage to the liver parenchyma, icterus catarrhalis, hepatitis epidemica, viral hepatitis (Engystol N in addition), acute parenchymatous hepatitis (mainly of toxic or retoxic origin), cholangitis, cholecystitis, cholelithiasis with and without colic. Injeel-Chol is a preparation to be frequently interposed in numerous phases, as the liver shows damage in very many

patients, above all in the retoxic phases. Alternation with, or the simultaneous administration of, Hepeel, Chelidonium-Homaccord and possibly also Galium-Heel is indicated. For suppurations (empyema), Injeel-Chol daily i.v., possibly with Traumeel  S.

The dosage is adjusted according to the disease, the symptoms and the stage of the illness.

Drops _ Injection solution Composition:

Drops: 100 g cont.: Ignatia D4, Ignatia D10, Ignatia D30, Ignatia D200, Moschus moschiferus D6, Moschus moschiferus D30, Moschus moschiferus D200 0.5g each. Contains 35 vol.-% alcohol.

Injection solution: 1.1 ml cont.: Ignatia D6, Ignatia D10, Ignatia D30, Ignatia D200, Moschus moschiferus D8, Moschus moschiferus D30, Moschus moschiferus D200 5.5 µl each.

Indications:

Depression, especially of exogenous origin; paradoxical symptoms; hysterical aphonia. Dosage:

Drops: In general, 10 drops 3 times daily. In convulsive disorders, initially 10 drops every 15 minutes, over a period lasting up to two hours. Long-term application of the preparation (over several months or longer) must be supervised by a therapist.

Injection solution: In convulsive disorders daily, otherwise 3-1 times weekly 1 ampoule i.m., s.c., i.d., i.v.

Package sizes:

Drops: Drop bottles containing 30 and 100 ml.

Injection solution: Packs containing 5, 10, 50 and 100 ampoules of 1.1 ml.

Pharmacological and clinical notes

Ignatia (St. Ignatius’ bean)

Lability of mood, tendency to weep, exogenous depression, globus hystericus, irrational symptoms, headache like a nail in the forehead.

Moschus moschiferus (glandular secretion from the male musk deer)

Fearfulness, hysteria, nervous excitability and restlessness accompanied by trembling, anxiousness with palpitations, aphonia.

Based on the individual homoeopathic constituents of Ignatia-Homaccord, therapeutic possibilities result for its application as nerve tonic for depression alternating with mania, contentiousness, climacteric neurosis (in addition to Nervoheel, Hormeel S and Klimakt-Heel), globus hystericus (after or in alternation with Ypsiloheel), aphonia, nervous irritability; often indicated for children who cry frequently (after Nervoheel, Viburcol, etc. or in alternation with them).

Auxiliary remedy for arteriosclerosis, when there is a tendency to weep without cause and there is numbness of the head with cephalalgia (frontal eminence).

Ignatia-Homaccord is indicated for asthma, emphysema, etc., and additionally in massive initial-dose therapy when the patient cannot breathe deeply (as if obstructed), possibly in association with the acids of the citric acid cycle i.v., as well as with Carbo vegetabilis-Injeel and Sulfur-Injeel S (orally and i.v.).

The dosage is adjusted according to the disease, the symptoms and the stage of the illness.

Drops Composition:

100 g cont.: Arsenum jodatum D6, Atropa belladonna D4, Scilla D4 20 g each; Cuprum aceticum D6 10 g; Causticum Hahnemanni D6 30 g. Contains 35 vol.-% alcohol.

Indications:

Coughs, e.g. chills and colds, spasmodic bronchitis, pleurisy.

Contraindications:

The preparation includes an iodine-containing ingredient. In cases of thyroid disorder with reduced iodine tolerance use only on the advice of a physician.

Side effects:

None known.

Interactions with other medication:

None known.

Dosage:

In general, 10 drops 3 times daily; for attacks of coughing 10 drops every 15 minutes, over a period lasting up to two hours.

Package sizes:

Drop bottles containing 30 and 100 ml.

Pharmacological and clinical notes

Arsenum jodatum (arsenic triiodide)

Dry, irritating cough, chronic nasal catarrh, dry coughs, bronchopneumonia, pleurisy. Atropa belladonna (deadly nightshade)

Barking cough, hoarseness, worsening at night. Scilla (squill)

Laryngeal catarrh, dry, severe cough, especially when lying down, cardiac insufficiency with congestive bronchitis.

Cuprum aceticum (copper acetate)

Pertussis, laryngospasms, asthenic pneumonia, hoarseness. Causticum Hahnemanni

Neck sore and raw, hoarseness, catarrh of the respiratory tract.

Based on the individual homoeopathic constituents of Husteel, therapeutical possibilities result for the treatment of acute catarrhal, irritating and tickling coughs; also coughs in asthma, emphysema, laryngitis, tracheitis and (chronic) bronchitis (Bronchalis-Heel, Tartephedreel, Drosera-Homaccord, Droperteel, etc.), irritating pleuritic coughs (with Bryaconeel, Ranunculus-Homaccord, etc.). For emphysema also to increase cardiac strength with Aurumheel N drops as auxiliary remedy. For pertussis, as auxiliary remedy.

For asthma with Drosera-Homaccord and Tartephedreel as well as a constitutional remedy (Psorinoheel, Schwef-Heel, Galium-Heel and, in particular, with the acids of  the citric acid cycle in ampoule form).

The dosage is adjusted according to the disease, the symptoms and the stage of the illness.

Drops _ Injection solution Composition:

Drops: 100 g cont.: Senecio nemorensis ssp. fuchsii D6, Acidum nitricum D4, Erigeron canadensis D3, Moschus moschiferus D6, Viburnum opulus D3, Pulsatilla pratensis D4, Sepia officinalis D6, Cyclamen europaeum D4, Ignatia D6, Thlaspi bursa pastoris D3 5 g each; Calcium carbonicum Hahnemanni D8, Aquilegia D4, Cypripedium calceolus var. pubescens D8, Origanum majorana D4, Nux moschata D6 10 g each. Contains 35 vol.-% alcohol.

Injection solution: 1.1 ml cont.: Senecio nemorensis ssp. fuchsii D6, Acidum nitricum D4, Erigeron canadensis D3, Moschus moschiferus D6, Viburnum opulus D3, Pulsatilla pratensis D4, Sepia officinalis D6, Cyclamen europaeum D4, Ignatia D6, Thlaspi bursa

pastoris D3 0.55 µl each; Calcium carbonicum Hahnemanni D8, Aquilegia D4, Cypripedium calceolus var. pubescens D8, Origanum majorana D4, Nux moschata D6 µl each.

Indications:

Functional disturbance of the female cycle. For the auxiliary medicinal treatment of sterility. To regulate the function of the endocrine glands.

Dosage:

Drops: In general, 10 drops 3 times daily.

Injection solution: Initially daily, otherwise 3-1 times weekly 1 ampoule i.m., s.c., i.d.,  i.v.

Package sizes:

Drops: Drop bottles containing 30 and 100 ml.

Injection solution: Packs containing 5, 10, 50 and 100 ampoules of 1.1 ml.

Pharmacological and clinical notes

Senecio nemorensis ssp. fuchsii (senecio)

Amenorrhoea, dysmenorrhoea, irregular menses with irritation of the bladder; after commencement of menses improvement of all disorders, haemostyptic action.

Acidum nitricum (nitric acid)

Ammoniacal fluor albus, incontinentia urinae, action on the mucous membranes, uterine haemorrhages, metrorrhagia.

Erigeron canadensis (fleabane)

Bright red haemorrhages with irritation of the bladder, menorrhagia, fluor albus.

Moschus moschiferus (glandular secretion of the male musk deer) Dysmenorrhoea, fainting and conditions of excitation.

Viburnum opulus (guelder rose) Dysmenorrhoea, abortus imminens. Pulsatilla pratensis (wind flower)

Amenorrhoea, migrating pains, fluor albus, constitutional remedy. Sepia officinalis (cuttlefish)

Hysteroptosis, downward pressure, chronic inflammation of the uterus and adnexa, acrid fluor albus, pruritus vulvae, exhaustion climacteric.

Cyclamen europaeum (cyclamen) Dysmenorrhoea, stabbing and irritating pains. Ignatia (St. Ignatius’ bean)

Irregular menses with spasmodic pains, lability of mood, tendency to weep, migraine. Thlaspi bursa pastoris (pennycress)

Metrorrhagia, menorrhagia, fluor albus, chronic cystitis, haemorrhages. Calcium carbonicum Hahnemanni (inner white part of the oyster shell)

Pre-menstrual headaches, colic, burning, irritation; displacement of uterus (tendency), uterine polypi, scrofulous glandular swelling.

Aquilegia vulgaris (columbine)

Dysmenorrhoea with pain on the left side, globus hystericus. Cypripedium calceolus var. pubescens (lady’s slipper) Nervous disorders in overstrained women, insomnia.

Origanum majorana (marjoram)

Nervous irritability, colic, galactagogue for nursing mothers with (painful) milk tumours. Nux moschata (nutmeg apple)

Abortus imminens, meteorism, nervous hyperactivity.

Hormeel S, due to its individual constituents, exerts a mildly stimulating action, in the combination effect (Bürgi), on the endocrine glands, especially on the hypophysis cerebri, through mobilization of the tropic hormones on the endocrine glands situated below (gonads, thyroid gland, suprarenal glands); further, also on the connective tissues, and it can, therefore, be applied as auxiliary remedy for the widest variety of indications in which there is a suspicion of hormonal dysfunction.

Based on the individual homoeopathic constituents of Hormeel S, therapeutical possibilities result for the treatment of functional disturbances in the female cycle, symptoms of ovarian and hypophyseal insufficiency, amenorrhoea, dysmenorrhoea (in the latter case, Spascupreel and Gynäcoheel in addition); as auxiliary medicinal treatment of sterility and in habitual miscarriage. Neurovegetative and psychosomatic disturbances (migraine, depression, nymphomania, in these cases possibly alternating with Ypsiloheel and Nervoheel). Female sterility (in combination with Gynäcoheel and Apis_Homaccord); climacteric (in addition to Klimakt-Heel and Metro-Adnex-Injeel).

As auxiliary remedy, Hormeel S is administered in oophoritis, adnexitis, salpingitis, para-, myo-, endometritis and colpitis (with Metro-Adnex-Injeel, Traumeel S and Gynäcoheel), in fluor albus (with Gynäcoheel and Lamioflur), in Kraurosis vulvae (with Mercurius-Heel S, Mezereum-Homaccord, possibly also Schwef-Heel, Sulfur-Injeel S, Klimakt-Heel, etc.).

Additional indications for Hormeel S are gynecological cystitis, various skin diseases such as neurodermatitis, rosacea, acne vulgaris juvenilis, as well as diseases of the mucous membranes (rhinitis, pharyngitis, laryngitis, laryngeal weakness (in addition to Phosphor-Homaccord and ), aphthous stomatitis, aphthe, struma parenchymatosa, hyperthyroidism) and loss of appetite in childhood (in addition to Lymphomyosot, Hepeel and Calcoheel). The dosage is adapted according to the disease, the clinical picture and the stage of the illness: In continuous treatment 10 drops 3-4 times daily. As massive initial-dose therapy to stimulate the hormones, 5-10 drops hourly, in addition 1 ampoule i.m., s.c., i.v., i.d., possibly with auxiliary remedies, at first daily, then later 1-3 times weekly. Hormeel S can cause the menses to begin prematurely, thereby, in our opinion, provoking increased haemorrhages.

Compositions

Tablets
1 tablet containing: Lycopodium clavatum D3, Chelidonium majus D6, Cinchona pubescens D3, Myristica fragrans D4 30 mg each; Silybum marianum D2, Phosphorus D6 15 mg each; Veratrum album D6 60 mg; Citrullus colocynthis D6 90 mg.

Injection solution
1.1 ml containing: Lycopodium clavatum D2, Chelidonium majus D6, China D2, Myristica fragrans D3 1.1 mg each; Silybum marianum D1, Phosphorus D5 0.55 mg each; Veratrum album D5 2.2 mg; Citrullus colocynthis D5 3.3 mg.

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Indications

Primary and secondary functional disorders of the liver; damaged liver.

Contraindications

Because of the constituent Celandine (Chelidonium) do not use during pregnancy and lactation. Do not use in case of hypersensitivity to Carduus marianus or other plants of the daisy family (Asteraceae) or in case of hypersensitivity to quinine.

Side effects

In rare cases, reactions of hypersensitivity, such as skin allergy or fever, may occur after exposure to drugs that contain quinine. In such cases, you must see a doctor.

Note

A quinine or quinidine sensitization may occur.

Interactions with other medication

None known.

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Dosage

Tablets
Standard dosage: Adults (and children 12 yrs and older): 1 tablet to be dissolved in the mouth 3× daily.

Injection solution
Standard dosage: Adults (and children 12 yrs and older): 1 ampoule 1 to 3× weekly. Hepeel injection solution may be administered by the s.c., i.d., i.m. or i.v. route.
Acute or initial dosage: Adults (and children 12 yrs and older): 1 ampoule daily, and then continue with standard dosage.

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Package sizes

Tablets: Packs containing 50 and 250 tablets. (47787)
Injection solution: Packs containing 10 and 100 ampoules of 1.1 ml each. (46791)

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Pharmacological notes

• Lycopodium clavatum: liver cirrhosis,1-8 cholecystitis,9 hepatitis,2-6,10-15 dermatoses,1,10,12,14,16-19 dermatitis,6,20 jaundice,2,14,19,21-25 abdominal distention,5,22,25-27 gastritis,1,5,6,14,21,25-28 eczema,1,10,12,14,16,17,19,23,25,28,29 and acne,6,7,10,19,25,27
• Chelidonium majus: liver cirrhosis,5,14,27,30,31 jaundice,1,10-12,15-22 abdominal distention,14,17,27,31 and gastritis,5,21,27,28
• Cinchona pubescens: gastritis,5-6,9,13,25 loss of appetite,4,11,12,14,16,25,28,31,37,38 liver cirrhosis,5-7,30-31 hepatitis,5,13,25,27,30,33 and cholecystitis,5,23
• Myristica fragrans: liver cirrhosis and loss of appetite,4-7,11,12,14,16,21,25,27,33,34,40,41
• Silybum marianum: liver cirrhosis,4-6,15-17,21,26,34 hepatitis,5-7,32,37 cholecystitis,6 and loss of appetite,4,6,9,16,26,30
• Phosphorus: liver cirrhosis,2-7,10-14,19,26,27,38,42 gastritis,5,11-14,18,22,36,43 hepatitis,4,10,12-14,19,25,26,40,44 and abdominal distention,7,16,18,22,25,27
• Veratrum album: abdominal distention,6,14-16,25-28,45,46 liver cirrhosis, hepatitis, loss of appetite,1,5,7,14,16,25,46 acne,6,7,14,27,30 and eczema
• Citrullus colocynthis: abdominal distention,6,7,14,16,25,38,41,46-48 loss of appetite,5,14,16,25,27 and jaundice,8,20

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Clinical notes

Because of the individual constituents of Hepeel, the medication can be offered for the following conditions:

1. Liver disorders: liver cirrhosis, hepatitis, and jaundice.
2. Other intestinal disorders: gastritis, abdominal bloating, gastrocardiac syndrome, cholangitis, and cholecystitis.
3. Loss of appetite.
4. Adjunctive therapy in chronic diseases, such as dermatoses, eczema, and acne vulgaris.

Note: Hepeel was recently examined for its in vitro effect on HepG2 hepatoblastoma cells. It has significant antioxidative, antiproliferative, and biochemical effects that point toward a hepatoprotective and tumerostatic action. Hepeel can be used in disorders such as cirrhosis, which has a potentially malignant outcome; the previously described evidence suggests the mechanism of its protective action.

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References

1. Gebhardt R. Antioxidative, antiproliferative and biochemical effects in HepG2 cells of a homeopathic remedy and its constituent plant tinctures tested separately or in combination. Arzneimittel-Forschung. 2003;53(12):823-830.
2. Alen TE. Handbook of Materia Medica and Homeopathic Therapeutics. 1st ed. New Delhi, India: Jain Publishers Ltd; 1889.
3. Farrington H. Homeopathy and Homœopathic Prescribing (Prepared for and Offered Only to Graduate Physicians). 1st ed. Philadelphia, PA: American Institute of Homœopathy; 1965.
4. Farrington EA. A Clinical Materia Medica Being a Course of Lectures Delivered at the Hahnemann Medical College of Philadelphia. 2nd ed. Philadelphia, PA: Hahnemann Publishing House; 1890.
5. Lilienthal SN. Homœopathic Therapeutics. 5th ed. Calcutta, India: S. Dey & Co.; 1925.
6. Monisan R. Desk Manual Companion to Physical Pathology. 1st ed. Albany, CA: Hahnemann Clinic Publishing; 1998.
7. Murphy R. Homeopathic Medical Repertory: A Modern Alphabetical Repertory. 1st ed. Pagosa Springs, CO: Hahnemann Academy of North America; 1993.
8. Schrayens F. Synthesis: Repertorium Homœopathicum Syntheticum. 5th ed. London, England: Homœopathic Book Publisher; 2004.
9. Royal G. Textbook of Homœopathic Materia Medica. 1st ed. Calcutta, India: Ray Publishing House; 1920.
10. Gupta RL. Directory of Diseases and Cures in Homœopathy: 1500 Authoritative References with Causes & Symptoms. Vol. 1-2. 1st ed. New Delhi, India: Jain Publishers Ltd; 1989.
11. Boericke W. Boericke’s Manual of Homœopathic Materia Medica with Repertory Comprising the Characteristics and Guiding Symptoms of All Remedies. 9th ed. Santa Rosa, CA: Boericke & Tafel; 1927.
12. Buck L. The Outlines of Materia Medica and a Clinical Dictionary. 1st ed. New Delhi, India: Jain Publishers Ltd; 1865.
13. Surt WH. Physiological Materia Medica. 5th ed. Chicago, IL: Gress & DeBridge; 1896.
14. Cleveland CL. Salient Materia Medica and Therapeutics. 1st ed. New Delhi, India: Jain Publishers Ltd; 1888.
15. Hering C. The Guiding Symptoms of our Materia Medica. Vol. 1-10. 1st ed. New Delhi, India: Jain Publishers Ltd; 1989.
16. Allen TF. The Encyclopedia of Pure Materia Medica: A Record of the Positive Effects of Drugs upon the Healthy Human Organism. Vol. 1-12. 1st ed. Phatak SR: Materia Medica of Homœopathic Medicines. 1st ed. London, England: Foulset & Vaughan Publishing; 1988.
17. Clarke JH. Clinical Lectures on Materia Medica. 3rd ed. London, England: Boericke & Tafel; 1899.
18. Dunham C. Lectures on Materia Medica. 3rd ed. Philadelphia, PA: Boericke & Tafel; 1934.
19. Hesoun P. The Homœopathic Treatment of Children: Pediatric Constitutional Types. 1st ed. Berkeley, CA: North Atlantic Books; 1991.
20. Vermeulen F. Prima – The Arcana of Materia Medica Illustrated. 2nd ed. The Netherlands: Emryss Publishers; 2002.
21. Blackwood AL. A Manual of Materia Medica, Therapeutics and Pharmacology (with Clinical Index). 2nd ed. New Delhi, India: World Homœopathic League; 1922.
22. Borland DM. Digestive Drugs. New Delhi, India: Jain Publishers Ltd; 1994.
23. Degrost E. Physical Examination and Observations in Homœopathy. 1st ed. Gent, Belgium: Homœopathic Book Service; 1992.
24. Farrington EA. Lesser Writings with Therapeutic Hints. 1st ed. Calcutta, India: Salzer & Co.; 1935.
25. Hoyne TS. Clinical Therapeutics. Vol. 1-2. New Delhi, India: Jain Publishers Ltd; 1979.
26. Hughes R. Cyclopaedia of Drug Pathogenesy. Vol. 1-4. 1st ed. New Delhi, India: World Homœopathic Link; 1891.
27. Vermeulen F. Concordant Materia Medica. 2nd ed. The Netherlands: Merija Publishers; 1997.
28. Kent JT. Lectures on Homœopathic Materia Medica. 10th ed. London, England; New York, NY; Philadelphia, PA: Boericke & Tafel; 1946.
29. Allen IF. A Primer of Materia Medica for Practitioners of Homœopathy. 1st ed. Philadelphia, PA: Boericke & Tafel; 1892.
30. Clarke JH. A Dictionary of Practical Materia Medica. Vol. 1-3. 3rd ed. Bradford, England: Health Science Press; 1977.
31. Hale EM. Special Symptomatology of the More Remedies. New Delhi, India: Jain Publishers Ltd.
32. Allen HC. Keynotes and Characteristics with Comparisons of Some of the Leading Remedies of the Materia Medica. 2nd ed. Wellingborough, England; Gregg Press Inc.; 1964.
33. Boger CMLA. Synoptic Key of the Materia Medica. 10th ed. New Delhi, India: Jain Publishers Ltd; 1931.
34. Rastogi D. Homœopathic Gems. 2nd ed. New Delhi, India: Jain Publishers Ltd; 1997.
35. Ales HC. The Therapeutics of Intermittent Fever. 2nd ed. New Delhi, India: Jain Publishers Ltd; 1884.
36. Choudhuri NM. A Study on Materia Medica and Repertory. New Delhi, India: Jain Publishers Ltd; 1929.
37. Murphy R. The Homœopathic Remedy Guide: 1200 Homœopathic and Herbal Remedies. 1st ed. Blacksburg, VA: HANA Press; 2000.
38. Lippe AJ. Keynotes and Red Line Symptoms of Materia Medica. New Delhi, India: Jain Publishers Ltd; 1998.
39. Mohanty N. Textbook of Homœopathic Materia Medica. 1st ed. New Delhi, India: Jain Publishers Ltd; 1997.
40. Farrington EA. Comparative Materia Medica. 3rd ed. New Delhi, India: Jain Publishers Ltd; 1983.
41. Leeser O. Textbook of Homœopathic Materia Medica: Inorganic Medicinal Substances. 1st ed. New Delhi, India: Jain Publishers Ltd; 1980.
42. Dewey WA. Practical Homeopathic Therapeutics. 3rd ed. Philadelphia, PA: Boericke & Tafel; 1934.
43. Hahnemann S. Materia Medica Pura. Vol. 1-2. 1st ed. London, England: Homœopathic Book Publishers; 1880.
44. Gibson DM. Studies of Homeopathic Remedies. 1st ed. Beaconsfield, England: Beaconsfield Publishers Ltd; 1987.
45. Dewey WA. Practical Homeopathic Therapeutics. 3rd ed. Philadelphia: Boericke & Tafel; 1934.
46. Hahnemann S. Materia Medica Pura. Vol 1–2. 1st ed. London: Homœopathic Book Publishers; 1880.
47. Gibson DM. Studies of Homeopathic Remedies. 1st ed. Beaconsfield: Beaconsfield Publishers; 1987.
48. Hahnemann S. The Chronic Diseases, Their Peculiar Nature and Their Homeopathic Cure. Vol 1–2. 2nd ed. New Delhi: Jain Publishers; 1981.
49. Gebhardt R. Antioxidative, antiproliferative and biochemical effects in HepG2 cells… Arzneimittel-Forschung. 2003;53(12):823-830.

Injection solution Composition:

Injection solution: 2.2 ml cont.: Hepar suis D8, Cyanocobalaminum D4, Duodenum  suis D10, Thymus suis D10, Colon suis D10, Vesica fellea suis D10, Pankreas suis D10, China D4, Lycopodium clavatum D4, Chelidonium majus D4, Carduus marianus D3, Histaminum D10, Sulfur D13, Avena sativa D6, Fel tauri D8, Natrium diethyloxalaceticum D10, Acidum alpha-ketoglutaricum D10, Acidum DL-malicum D10, Acidum fumaricum D10, Acidum alpha-liponicum D8, Acidum oroticum D6, Cholesterinum D10, Calcium carbonicum Hahnemanni D28, Taraxacum officinale D4, Cynara scolymus D6, Veratrum album D4 22 µl each.

Indications:

Stimulation of the detoxicating function of the liver in acute and chronic diseases of the liver/gall, e.g. cholangitis and cholecystitis; in functional disorders of the liver of toxic origin as cause or result of other diseases, in hypercholesteremia, erythematodes,  toxic exanthema, dermatosis and dermatitis, neurodermitis and for the stimulation of the liver cell functioning.

Dosage:

In general, 1 ampoule i.m., s.c., i.d., or, if necessary, i.v., 3-1 times weekly.

Package sizes:

Packs containing 5, 10, 50 and 100 ampoules of 2.2 ml.

Pharmacological and clinical notes

Cyanocobalaminum (Vitamin B12)

Damage to the liver parenchyma, disturbance of the detoxicating hepatic function, disturbance of the fat and carbohydrate metabolism.

Hepar suis (liver)

Stimulation of the detoxicating hepatic function. Duodenum suis (duodenum)

Duodenitis, duodenal ulcers, gastrocardiac syndrome. Thymus suis (thymus gland)

Stimulation of the lymphatic system, neoplasm phases, disturbances to growth and development.

Colon suis (large intestine)

Stimulates the detoxicating and secretory processes, intestinal stasis, intestinal tenesmus, colitis mucosa et ulcerosa.

Vesica fellea suis (gall bladder) Chronic cholangitis and cholecystitis. Pankreas suis (pancreas)

Pancreopathy, chronic enteritis, marasmus, cachexia. China (Peruvian bark)

Remedy for debility, flatulent colic, biliary colic, enlargement of liver, gastroduodenitis. Lycopodium clavatum (club-moss)

Diseases of the hepatic and cystic ducts, loss of appetite or Iycorexia, meteorism, pale yellowish complexion.

Chelidonium majus (celandine)

Cholelithiasis, cholecystitis, cholangitis, biliary colic, pain under the right shoulder blade, hepatopathy.

Carduus marianus (milk thistle)

Liver damage, congestion of the portal vein, biliary colic, haemorrhoids. Histaminum (histamine)

To support the detoxicating function, increased glandular secretion, eczema and dermatosis.

Sulfur (sulphur)

Reagent in all chronic diseases; cellular activity is influenced catalytically. Avena sativa (common oats)

Nervous exhaustion; recommended for manias. Fel tauri (ox bile)

Diseases of the liver and gall bladder, cholelithiasis. Natrium diethyloxalaceticum (sodium oxalacetate)

Active factor of the citric acid cycle and of redox systems; intolerance to fats and albumin.

Acidum alpha-ketoglutaricum (a-ketoglutaric acid)

Active factor of the citric acid cycle and of redox systems; feeling of weakness. Acidum DL-malicum (malic acid)

Active factor of the citric acid cycle and of redox systems; promotes detoxication. Acidum fumaricum (fumaric acid)

Active factor of the citric acid cycle and of redox systems; conditions of exhaustion. Acidum alpha-liponicum (thioctic acid)

Coenzyme in the decomposition of pyruvic acid. Orotic acid (lactic acid)

Liver damage. Cholesterinum (cholesterol)

Cholelithiasis, cirrhosis of the liver, cancer of the liver.

Calcium carbonicum Hahnemanni (inner white part of the oyster shell)

Conditions of exhaustion, pain in the epigastrium upon contact, persistent flatulence, biliary colic.

Taraxacum officinale (dandelion)

Cholecystopathy, hepatopathy with and without jaundice, meteorism, flatulence, congestion of the portal vein, gastritis.

Cynara scolymus (globe artichoke)

Stimulation of the detoxicating hepatic function and of diuresis; tonic. Veratrum album (white hellebore)

Affections starting feverishly, chronic vomiting, diarrhoea, conditions of collapse.  Based    on the individual  homoeopathic constituents of Hepar compositum, therapeutical possibilities result for the stimulation of the detoxicating hepatic function

in acute and chronic effectations of the liver and gall bladder, e.g. for cholangitis, cholecystitis; also, however, of disturbances of the hepatic function of toxic origin: cirrhosis of the liver, hepatitis epidemica, as well as disturbances of the hepatic function as the cause or consequence of other diseases; for hypercholesterinaemia, erythematosus, toxic exanthema, dermatosis and dermatitis, neurodermatitis, and to stimulate the functions of the liver cells.

The active substances combined in Hepar compositum, such as Vitamin B12, organ extracts and homoeopathic medicaments particularly aimed at the hepatic functions, complement themselves synergistically with potentiated action.

The action of Hepar compositum can be increased by the intermediate administration of Ubichinon compositum ampoules, Coenzyme compositum ampoules and possibly Thyreoidea compositum (antineoplastic action).

If the disorders are located more in the left side of the epigastrium or alternate from side to side, intermediate injections of Momordica compositum, Ceanothus- Homaccord, possibly also Leptandra compositum, and if there is a suspicion of neoplasia, also Podophyllum compositum as well as Viscum compositum (medium, forte), etc. are indicated.

Alternating injections with Hepeel, Injeel-Chol and possibly Chelidonium-Homaccord exert a favourable action; for suitable symptoms, possibly also with Nux vomica- Homaccord. The latter preparations should also be administered, according to the symptoms in each case, orally with Chelidonium-Homaccord.

Alternating remedies for intestinal stasis are Leptandra compositum, Momordica compositum, Nux vomica-Homaccord and Papaver-Injeel forte, and possibly also Dioscorea-Injeel forte.

The dosage is adjusted according to the disease, the clinical picture and the stage of the illness: initially 1 ampoule s.c., i.m., possibly i.v. 3 times weekly; in the further course of treatment 1 ampoule s.c. only once to twice weekly, alternating with auxiliary remedies.

Ointment Composition:

100 g cont.: Hamamelis virginiana Ø 10.0 g. Ointment base: hydrophilic ointment (DAB 10) cont.: emulsifying cetylstearyl alcohol, ethanol, purified water, liquid paraffin, soft white paraffin, preserved with 14.5 Vol.-% ethanol.

Indications:

Varicosis, haemorrhage of the skin and the mucosa.

Contraindications:

Hypersensitivity to constituents of the ointment base.

Side effects:

None known.

Interactions with other medication:

None known.

Method of application:

In general, spread over the affected parts of the skin once to twice daily. Package sizes:

Tube containing 50 g of ointment.

Pharmacological and clinical notes

Hamamelis virginiana (witch-hazel)

Venous stasis, varicose veins, (thrombo-)phlebitis, crural ulcers, haemorrhoids, venous haemorrhages.

Drops _ Injection solution Composition:

Drops: 100 g cont.: Hamamelis virginiana D2, Hamamelis virginiana D30, Hamamelis virginiana D200 0.8g each; Carduus marianus D6, Carduus marianus D30, Carduus marianus D200 0.2 g each. Contains 35 vol.-% alcohol.

Injection solution: 1.1 ml cont.: Hamamelis virginiana D4, Hamamelis virginiana D30, Hamamelis virginiana D200 8.8 µl each; Carduus marianus D6, Carduus marianus D30, Carduus marianus D200 2.2 µl each.

Indications:

Venous stasis, varicose eczema, thrombophlebitic conditions.

Dosage:

Drops: In general, 10 drops 3 times daily. In acute disorders, initially 10 drops every 15 minutes, over a period lasting up to two hours. Long-term application of the  preparation (over several months or longer) must be supervised by a therapist.

Injection solution: In acute disorders daily, otherwise 3-1 times weekly 1 ampoule i.m., s.c., i.d., i.v.

Package sizes:

Drops: Drop bottles containing 30 and 100 ml.

Injection solution: Packs containing 5, 10, 50 and 100 ampoules of 1.1 ml.

Pharmacological and clinical notes

Hamamelis virginiana (witch-hazel)

Venous stasis, varicose veins, (thrombo-)phlebitis, crural ulcers, haemorrhoids, venous haemorrhages.

Carduus marianus (milk thistle)

Remedy for disorders of the hepatic functions, varicose syndrome.

Based on the individual homoeopathic constituents of Hamamelis-Homaccord, therapeutic possibilities result for the treatment of venous stasis, varicose syndrome, crural ulcers, sural spasms (in addition to Spascupreel and Veratrum-Homaccord), sensation of heaviness in the legs, intermittent claudication (in addition to Arteria-Heel and Circulo-Injeel), phlebitis, thrombophlebitis (in addition to Belladonna-Homaccord and possibly Traumeel S, Cruroheel S), oedema of the legs (with Apis_Homaccord).

Erythema exsudativum multiforme et nodosum (in addition to Abropernol, Cruroheel S, Traumeel S tablets and possibly Osteoheel S); is often needed in addition to Cinnamomum-Homaccord N for haemorrhages. It has an absorbing action in cases of haematomas, ecchymosis, haemarthrosis (in addition to Traumeel S) orally and intradermal Iocally. The dosage is adjusted according to the disease, the symptoms and the stage of the illness: 10 drops 3-4 times daily. In conditions of pain (leg) or thrombophlebitis, firstly an aggregate dosage of 10 drops every 15-30 minutes. 1 ampoule 1-3 times weekly; for thrombophlebitis (with Belladonna-Homaccord, etc.) initially 1 ampoule daily i.m., s.c., i.d., i.v., otherwise 1-3 times weekly.

Drops Composition:

100 g cont.: Apis mellifica D4, Ammonium bromatum D4, Lilium tigrinum D4, Aurum jodatum D12, Crabro vespa D4, Helonias dioica D4, Palladium metallicum D12, Platinum metallicum D12, Naja naja D12 10 g each; Melilotus officinalis D3, Viburnum opulus D2 5 g each. Contains 35 vol.-% alcohol.

Indications:

Inflammatory conditions of the female genital organs, e.g. adnexitis (ovaritis, salpingitis), parametritis, myometritis, endometritis, colpitis.

Contraindications:

The preparation includes an iodine-containing ingredient. In cases of thyroid disorder with reduced iodine tolerance use only on the advice of a physician.

Side effects:

None known.

Interactions with other medication:

None known.

Dosage:

In general, 10 drops 3 times daily. In acute disorders, initially 10 drops every 15 minutes, over a period lasting up to two hours.

Package sizes:

Drop bottles containing 30 and 100 ml.

Pharmacological and clinical notes

Apis mellifica (honey bee)

Oedema: ovaritis, right; hypersensitivity, nervousness. Ammonium bromatum (ammonium bromide)

Calming action, neuralgic headaches. Lilium tigrinum (tiger lily)

Fluor albus, dysmenorrhoea, uterus descensus, nervous cardiac disturbances, colpitis. Aurum jodatum (gold iodide)

Myomas, ovarial cysts, arteriosclerosis. Crabro vespa (hornet)

Ovaritis, left.

Helonias dioica (stud flower)

Conditions of exhaustion, uterus descensus et prolapsus, endometritis, remedy for women’s ailments.

Palladium metallicum (palladium) Ovaritis, ovarial cysts.

Platinum metallicum (platinum)

Increasing    and    decreasing    pains, mental changes, menorrhagia, myomatous haemorrhages, pruritus vulvae.

Naja naja (spectacled snake)

For affections of the ovaries, pain extending to the heart. Melilotus officinalis (melilot)

Venous remedy, dysmenorrhoea, ovaralgia. Viburnum opulus (guelder rose) Dysmenorrhoea.

Based on the individual homoeopathic constituents of Gynäcoheel, therapeutic possibilities result for the treatment of inflammatory processes (reaction phases) and functional diseases of the female germinal tissue (germinoderm); ovaritis, salpingitis, para-, myo-, endometritis, colpitis, possibly in combination with Metro-Adnex-Injeel, Hormeel S and Traumeel S, possibly Arnica-Heel and Apis_Homaccord; fluor albus (combination with Lamioflur, Hormeel S and Traumeel S, possibly Klimakt-Heel); kraurosis vulvae (in combination with Mercurius-Heel S, Hormeel S, Mezereum- Homaccord, etc.); dysmenorrhoea (with Spascupreel); amenorrhoea (with Hormeel S); after gynecological haemorrhages (in this case, firstly Cinnamomum-Homaccord N orally and i.m., s.c., i.v.).

Female sterility (combination with Hormeel S and Apis_Homaccord, possibly also Arnica-Heel and Agnus castus-Injeel). As adjuvant experimentally for myomas (in addition: Aurum jodatum-Injeel forte, Hydrastis-Injeel forte and Metro-Adnex-Injeel, possibly also Sulfur-Injeel forte S as mixed injection i.v., as well as Psorinoheel, Strumeel forte, Hormeel S and Galium-Heel). As auxiliary remedy likewise to be tried for alopecia and rosacea (in association with Hormeel S, Cruroheel S and Traumeel  S), as well as for habitual abortion and for frigidity. Especially to be recommended are additional injections of Ovarium compositum.

Gynäcoheel, due to its composition, acts not only in checking inflammation but also exerts a function-regulating influence on the whole female genital sphere, in which case it is combined, according to the indications, with other biotherapeutic agents, several preparations being administered in 1-2-4-hourly alternation or simultaneously. The dosage is adjusted according to the disease, the clinical picture and the stage of the illness: 10 drops 3 times daily before meals. In painful conditions or acute inflammation, initially massive initial-dose therapy of 10 drops every 15 minutes, for 2-3 hours.

An important auxiliary remedy for conditions of gynecological inflammation and functional disorders is Metro-Adnex-Injeel (i.m., s.c., i.v. and over the os sacrum – segmental therapy).

Administration in cases of sterility:

Gynäcoheel 8-10 drops at 8 a.m. and 4 p.m. Hormeel S 8-10 drops at 10 a.m. and 6 p.m.

Apis_Homaccord 8-10 drops at 12 noon and 8 p.m. or 5-10 drops of each of these preparations taken together 2-3 times daily.

If no result is seen, Apis_Homaccord should be exchanged for Arnica-Heel, as well as Ovarium suis-Injeel and Placenta suis-Injeel mixed or alternating once to twice weekly for therapy-resistant functional disorders, in addition.

Tablets _ Injection solution Composition:

Tablets: 1 tablet cont.: Aconitum napellus D4 120 mg; Bryonia cretica D4, Lachesis mutus D12 60 mg each; Eupatorium perfoliatum D3, Phosphorus D5 30 mg each.

Injection solution: 1.1 ml cont.: Aconitum napellus D3 4.4 µl; Eupatorium perfoliatum D2, Phosphorus D4 1.1 µl each; Lachesis mutus D11, Bryonia cretica D3 2.2 µl each. Indications:

Tablets: Influenza and influenzal infections and for the stimulation of the endogenic defence system in other feverish infectious diseases.

Injection solution: Influenza and influenzal infections.

Dosage:

Tablets: In general, 1 tablet to be dissolved under the tongue 3-5 times daily. In acute disorders, 1 tablet every 15 minutes, over a period lasting up to two hours.

Injection solution: In acute disorders daily, otherwise 3-1 times weekly 1 ampoule i.m., s.c., i.d., i.v.

Package sizes:

Tablets: Packs containing 50 and 250 tablets.

Injection solution: Packs containing 5, 10, 50 and 100 ampoules of 1.1 ml.

Pharmacological and clinical notes

Aconitum napellus (monkshood)

Chills, influenza; fever with hot, dry skin; neuralgia, inflammatory rheumatism, angina pectoris with anxiety.

Bryonia cretica (bryony)

Inflammation of all serous membranes, coughing when entering a warm room, thirst, rheumatic pains.

Lachesis mutus (bushmaster)

Inattention to worsening condition, accumulation of mucus, e.g. congestive bronchitis, sensation of globus, angina tonsillaris, bluish-red swelling.

Eupatorium perfoliatum (thoroughwort)

Influenzal infections/influenza with pains in the limbs; coughs with excruciating pain in the chest and headaches.

Phosphorus (phosphorus)

Remedy for affections of the parenchyma, bronchopneumonia, laryngitis with hoarseness, damage to the liver parenchyma.

Based on the individual homoeopathic constituents of Gripp-Heel, therapeutical possibilities result for the treatment of influenza and catarrhal influenzal infections in any stage and in patients of any age. Further, other feverish (infectious) diseases such as angina, otitis media, bronchitis, tracheitis, etc.

Irrespective of which particular organotropism (organotropy to the upper parts of the respiratory tract, such as the nose and pharynx, pneumo-, cardio-dermato-, entero- or neurotropy) or which microorganism causing influenza is present, an increase in the body’s own defences is always indicated, which is achieved by means of Gripp-Heel (orally and/or parenterally).

In this connection, in the reversal effect according to Arndt-Schulz, Aconitum exerts a specially stimulating action on the haemoderm (abatement of chilliness), in addition rapidly relieving neuralgic disorders and circulatory lability, while Eupatorium eliminates pains in the joints and the feeling of exhaustion. The content of Lachesis mutus (septic infections, tendency towards haemolysis), Bryonia cretica (thirst, irritation from coughing, retrosternal pain, diseases of the serous membranes such as pleuritis) and Phosphorus (petechiae, elective effect on the lungs in preventing pneumonia) broadens the therapeutical spectrum of Gripp-Heel according to Burgi’s principle, perfecting the preparation effectively. The dosage is adjusted according to the disease, the clinical picture and the stage of the illness: in fever and to cut the disease short, at the start of therapy 1 tablet every 15 minutes for 2-3 hours, after which, transition to 1 tablet 3 times daily. As influenza prophylaxis in periods of epidemic, 1 tablet 3 times daily. In primary or secondary serious stages, in addition 1-2 ampoules daily i.m., s.c., i.d., i.v., preferably mixed with Engystol N and/or with Traumeel S (mixed injections to avoid excessive reactions, i.m. or s.c.), as long as fever remains; possibly intermediate injections of Echinacea compositum S.

The intradermal neural application of Gripp-Heel is particularly indicated for  pains in the joints. For children, it is recommended that only i.m. or s.c. injections of Gripp-Heel ampoules should be given.