Methylglyoxal

The attenuations are prepared from a solution of methylglyoxal, C₃ H₄O₂, MW: 72.1.

It is produced in small quantities during metabolic processes (Karrer), possesses a carbonyl group and an aldehyde group and is therefore ideally suited for transfer of hydrogen and catabolism of toxic amino-groups from azomethin compounds. Indi- cated in cellular phases, and particularly in degeneration and neoplasm phases.

The drug picture of Methylglyoxal was composed in September 1997 by David Riley, M.D., Santa Fe (New Mexico), USA.

The most important symptoms from David Riley’s drug proving were:

Essential Characteristics

Increased energy. Desires or aversion to chocolate. Desires sweets. Headaches. Aversion to company. Heartburn or burning pain of the stomach. Strong odor to the urine.

Mind

Aversion to company with a desire for reflection and this aversion begins on wak- ing in the morning. Dreams that are anxious, fearful, and of being pursued. Weeping more easily than normal.

Generalities

Cold symptoms appear but the cold does not come on. Increased energy especial- ly in the evening. Food desires fats like butter and mayonnaise, chicken liver, choco- late and sweets, cold drinks, and sour fruit. Aversion to sweets even during the pre- menstrual time.

Head

Pimples on the forehead. Headaches that are pressing at the vertex when spine seems misaligned or pounding between the eyes.

Eye

Strong desire to close the eyes as if drugged even though sound sleep during the previous night. Warm sensation in the right eye. Itching and swelling of the upper left eye lid as from hayfever.

Nose

Sneezing as if from hayfever. Tickling inside the nose. Sniffling in the morning.

Face

Tightness and tension of the facial muscles improves.

Mouth

Dryness in the morning.

Throat

Sore throat on waking that is associated with a tickle in the nose. Swollen sensa- tion of the throat that is worse when swallowing.

Stomach

Decreased appetite. Distention with acid stomach. Heartburn and acid indiges- tion. Nausea with stomach pain. Squeezing pain that is worse after eating or drink- ing that is like a rope being tightened under the diaphragm and rib cage.

Abdomen

Distention without flatus. Squeezing pain in the hypochondrium worse after drink- ing or eating.

Rectum

Stabbing and stitching pain during constipated stool that extends upward.

Stool

Loose stools that are not formed but that are not watery.

Urine

Strong odor to the urine that is acrid or like horse’s urine.

Genitalia, Female

Increased flow of menstrual blood.

Back

Tension in the back muscles is relieved. Sore pain in the thoracics.

Extremities

Stiffness in the legs on waking in the morning. Pain that is burning in the thigh or sore in the legs and calves.

Sleep

Tossing and turning in bed. Overpowering sleepiness at noon after sound sleep the previous night.

Perspiration

Perspiration that is more salty than usual and that leaves deposits of salt on the skin. Sweating at night.