Manganum Gluconicum – Manganese Gluconate

The attenuations are prepared from Manganese(II)-gluconate,

the Manganese(II)salt of D-gluconic acid, C₁₂H₂₂MnO₁₄ · 2 H₂O, MW: 481.2.

Manganese salts have a strong enzyme action, e.g. in the Citric Acid cycle, in which energy in the mitochondria is obtained from glucose. By providing man- ganese salts in the form of an organic compound (with gluconic acid) the opportuni- ty is offered for rapid entry into the cell. Gluconic acid occupies a key position in the oxidation of glucose via the pentose-phosphate cycle (Warburg-Dickens-Horecker schema)

Manganese gluconate is not usually given as a single remedy, but in combination with other enzyme-activating factors.