Engystol®

Written by

Urenus

in

TABLETS – INJECTION SOLUTION

Compositions:

Tablets: 1 tablet containing: Vincetoxicum hirundinaria D6, Vincetoxicum hirundinaria D10, Vincetoxicum hirundinaria D30 75 mg each; Sulfur D4, Sulfur D10 37.5 mg each.
Injection solution: 1.1 ml containing: Vincetoxicum hirundinaria D6, Vincetoxicum hirundinaria D10, Vincetoxicum hirundinaria D30 6.6 mg each; Sulfur D4, Sulfur D10 3.3 mg each.

Indications:

To activate the nonspecific immune system, particularly in influenzalike infections and viral diseases in general.

Contraindications:

Known allergy (hypersensitivity) to one or more of the ingredients.

Side effects:

Allergic (hypersensitivity) reactions (e.g. skin allergies, (injection solution:) redness/swelling at the injection site) may occur in very rare cases (i.e. affects less than 1 in 10,000 users)

Interactions with other medication:

None known.

Dosage:

Tablets:
Standard dosage: Adults (and children 12 yrs. and older): 1 tablet to be dissolved in the mouth 3x daily.
Acute or initial dosage: Adults (and children 12 yrs. and older): 1 tablet every 1/2 to 1 hr., up to 12x daily, and then continue with standard dosage.

Injection solution:

Standard dosage: Adults (and children 12 yrs. and older): 1 ampoule 1 to 3x weekly. Engystol injection solution may be administered by the s.c., i.d., i.m. or i.v. route.
Acute or initial dosage: Adults (and children 12 yrs. and older): 1 ampoule daily, and then continue with standard dosage.

Package sizes:

Tablets: Packs containing 50 and 250 tablets. (9830)
Injection solution: Packs containing 10 and 100 ampoules of 1.1 ml each. (8546)

Pharmacological notes

Vincetoxicum hirundinaria: viral infections, mononucleosis (1,2), and mumps (2).
Sulfur: influenza (3,4), epidemic and sporadic fevers (5), continued fevers (4,6,7), pneumonia (6–14), hepatitis (4,7,11,15,16), aphthae (ulcerated or nonulcerated) (4,7,9,11–13,17–21), mononucleosis (16), urticaria (4,7,12,13,15,16,22,23), pruritus vulvae (4), furunculosis (4,5,7,12,13,19,24–26), eczema (4,6,7,9,10,12–14,19–21,25,27), hay fever (15,16), bronchitis (6,7,12,13,24,27–29), pertussis (7,16,30), asthma (4–7,9,10,12–14,17,19–21,27,29,31), heart palpitations (4–6,13,28,29,32,33), endocarditis (34), migraine (10,16,22,26,35), neuralgia (4,6,7,9,13,17,28,29,31), and bronchiectasis (36).

Clinical notes

Because of the individual constituents of Engystol, the medication can be offered for the following conditions:

  1. Viral infection of all kinds: influenzalike infections, viral pneumonia, viral hepatitis (adjuvant therapy), and aphthous ulceration (reactivation of a viral disease, such as Epstein-Barr virus infection)
  2. Skin disease: urticaria, pruritus vulvae, eczema, and furunculosis
  3. Respiratory system conditions: hay fever, bronchitis, bronchiectasis, pertussis, pneumonia, and asthma (adjuvant therapy)
  4. Circulatory system conditions: palpitations and endocarditis (adjuvant therapy)
  5. Nervous system conditions: migraine and neuralgia

Note:

Engystol exerts its effect mainly on the immune system and the sympathetic nervous system. Apart from having an effect on neutrophil proliferation in vitro, which is synergistically enhanced by Gripp-Heel (37), a recent study (38) of Engystol demonstrated the antiviral effect of Engystol on adenovirus and respiratory syncytial virus. In clinical studies, Engystol lowered the severity of symptoms and enhanced resolution of influenzalike infections when given prophylactically (39). The sympathomimetic effect of Engystol is achieved through the asclepiadic acid in vincetoxin, which acts similarly to aconitine. It has a powerful effect on the sympathetic nervous system. Reckeweg (1) postulated that homeopathic Sulfur may regenerate sulfhydryl-containing enzymes, which are powerful antioxidants and free radical scavengers. Thus, it also may have a deep action on the extracellular matrix.

Therapeutic notes:

Because of the sympathomimetic effect of Engystol, caution should be exercised when it is injected into nervous individuals with sympathetic overload because it contributes to the symptoms.

References

  1. Reckeweg H-H. Homoeopathia Antihomotoxica-Symptomen-und Modalitätenverzeichnis mit Arzneimittellehre. Vol 1-2. 6th ed. Baden-Baden, Germany: Aurelia Verlag; 1999.
  2. Schmid F, Hamalcik P. Antihomotoxische Medizin-Band II: Homöopathische Antihomotoxica. Vol 2. 1st ed. Baden-Baden, Germany: Aurelia Verlag; 1996.
  3. Baehr B. The Science of Therapeutics According to the Principles of Homoeopathy. Vol 1-2. 1st ed. New Delhi, India: World Homoeopathic Links; 1980.
  4. Hoyne TS. Clinical Therapeutics. Vol 1-2. New Delhi, India: Jain Publishers Ltd; 1979.
  5. Hahnemann S. The Chronic Diseases, Their Peculiar Nature and Their Homoeopathic Cure. Tafel LH, trans-ed. Vol 1-2. 2nd ed. New Delhi, India: Jain Publishers Ltd; 1981.
  6. Farrington EA. Lesser Writings With Therapeutic Hints. 1st ed. Calcutta, India: Salzer & Co; 1935.
  7. Hering C. The Guiding Symptoms of Our Materia Medica. Vol 1-10. 1st ed. New Delhi, India: Jain Publishers Ltd; 1989.
  8. Allen HC. Keynotes and Characteristics With Comparisons of Some of the Leading Remedies of the Materia Medica. 1st ed. Wellingborough, England: Thorsons Publishers Ltd; 1898.
  9. Allen TF. Handbook of Materia Medica and Homeopathic Therapeutics. 1st ed. New Delhi, India: Jain Publishers Ltd; 1889.
  10. Boger CM. A Synoptic Key of the Materia Medica. 1st ed. New Delhi, India: Jain Publishers Ltd; 1931.
  11. Buck H. The Outlines of Materia Medica and a Clinical Dictionary. 1st ed. New Delhi, India: Jain Publishers Ltd; 1865.
  12. Choudhuri NM. A Study on Materia Medica and Repertory. 2nd ed. New Delhi, India: Jain Publishers Ltd; 1929.
  13. Clarke JH. A Dictionary of Practical Materia Medica. Vol 1-3. 3rd ed. Bradford, England: Health Science Press; 1977.
  14. Degroote F. Physical Examination and Observations in Homoeopathy. 1st ed. Gent, Belgium: Homeoden Bookservice; 1992.
  15. Schroyens F. Synthesis. Repertorium Homeopathicum Syntheticum. 9th ed. London, England: Homeopathic Book Publishers; 2004.
  16. Murphy R. Homeopathic Medical Repertory: A Modern Alphabetical Repertory. 1st ed. Pagosa Springs, CO: Hahnemann Academy of North America; 1993.
  17. Allen TF. The Encyclopedia of Pure Materia Medica: A Record of the Positive Effects of Drugs Upon the Healthy Human Organism. Vol 1-12. 1st ed. Ridgewood, NJ: Gregg Press Inc; 1964.
  18. Allen TF. A Primer of Materia Medica for Practitioners of Homoeopathy. 1st ed. Philadelphia, PA: Boericke & Tafel; 1892.
  19. Kent JT. Lectures on Homeopathic Materia Medica. 4th ed. London, England; New York, NY; Philadelphia, PA: Boericke & Tafel; 1946.
  20. Lilienthal S. Homoeopathic Therapeutics. 5th ed. Calcutta, India: Sett Dey & Co; 1925.
  21. Lippe A. Keynotes and Red Line Symptoms of Materia Medica. New Delhi, India: Jain Publishers Ltd; 1998.
  22. Murphy R. The Homeopathic Remedy Guide: 1200 Homeopathic and Herbal Remedies. 1st ed. Blacksburg, VA: HANA Press; 2000.
  23. Vermeulen F. Prisma – The Arcana of Materia Medica Illuminated. 2nd ed. Haarlem, the Netherlands: Emryss Publishers; 2002.
  24. Blackwood AL. A Manual of Materia Medica, Therapeutics and Pharmacology (With Clinical Index). 2nd ed. New Delhi, India: World Homoeopathic Links; 1922.
  25. Leeser O. Textbook of Homoeopathic Materia Medica: Inorganic Medicinal Substances. 1st ed. New Delhi, India: Jain Publishers Ltd; 1980.
  26. Vermeulen E. Concordant Materia Medica. 2nd ed. Haarlem, the Netherlands: Merlijn Publishers; 1997.
  27. Burt WH. Physiological Materia Medica. 5th ed. Chicago, IL: Gross & Delbridge; 1896.
  28. Farrington EA. A Clinical Materia Medica. 2nd ed. Philadelphia, PA: Hahnemann Publishing House; 1890.
  29. Farrington H. Homeopathy and Homeopathic Prescribing. 1st ed. Philadelphia, PA: American Institute of Homeopathy; 1965.
  30. Royal G. Textbook of Homeopathic Materia Medica. 1st ed. Calcutta, India: Roy Publishing House; 1920.
  31. Hughes R, Dake JP. A Cyclopaedia of Drug Pathogenesy. Vol 1-4. 1st ed. New Delhi, India: World Homoeopathic Links; 1891.
  32. Boericke W. Pocket Manual of Homoeopathic Materia Medica With Repertory. 9th ed. Santa Rosa, CA: Boericke & Tafel; 1927.
  33. Hahnemann S. Materia Medica Pura. Vol 1-2. 1st ed. London, England: Homeopathic Book Publishers; 1880.
  34. Poirier I. Homoeopathic Treatment of the Diseases of Heart. Mukerjee RK, trans-ed. 1st ed. New Delhi, India: World Homoeopathic Links; 1982.
  35. Phatak SR. Materia Medica of Homoeopathic Medicines. 1st ed. London, England: Foxlee-Vaughan Publishers; 1988.
  36. Paige HW. Diseases of the Lungs, Bronchi and Pleura. New Delhi, India: Jain Publishers Ltd; 1988.
  37. Wagner H, Jurcik K, Doenicke A, Behrens N. Influence of homeopathic drug preparations on the phagocytosis capability of granulocytes: in-vitro tests and controlled single-blind studies. Biol Ther. 1993;11(1):43–49.
  38. Oberbaum M, Glatthaar-Saalmüller B, Stolt P, Weiser M. Antiviral activity of Engystol: an in vitro analysis. J Altern Complement Med. 2005;11(5):855–862.