Procainum compositum

Injection solution Composition:

Injection solution: 2.2 ml cont.: Viscum album D4, Ginseng D4, Artemisia abrotanum D4, China D6, Berberis vulgaris D6 22 µl each; Procainum hydrochloricum D2 1.1 ml. Indications:

Support of the defensive system, particularly of the sympathetic nerve and the anterior lobe of the pituitary gland/adrenal cortex system. For revitalisation with all types of developments in cellular phases; the pre-cancerous state.

Contraindications:

Known allergy to procaine, benzoic acid and sulphonamide. Cross-hypersensitivity to substances with chemical structures similar to

procaine (e.g. local ester anaesthetics and parabens) cannot be excluded. Concurrent treatment with sulphonamides or cholinesterase inhibitors. Pseudocholinesterase deficiency. Myasthenia gravis. During pregnancy Procainum compositum should only be used for carefully selected indications.

Side effects:

Parenteral administration: Partly dependent on dose and speed of injection, central nervous disturbances, excitability, breathing difficulties, bronchospasm, muscle tremor up to generalised cramps, nausea, vomiting, urticaria, mucosal oedema, exanthem, drop of blood pressure, tachycardia or bradycardia, anaphylactic shock and renal failure. Some cases have been fatal. Postmenopausal genital bleeding has been observed. Local reactions at the site of intramuscular or subcutaneous injection are uncommon, but occasionally swelling, oedema, erythema, papulovesicular eczema, and superficial or deep necrosis and haematoma formation have been seen at the site of injections. Local allergies and pseudoallergic reactions to procaine in the form of contact dermatitis accompanied by erythema, pruritus extending to formation of blisters may occur. In case of cutaneous manifestation of procaine allergy, allergic reactions may also occur after administration of sulphonamides or oral hypoglycaemic agents. Procainum compositum injections in the head/neck area are associated with  an increased risk of symptoms of central nervous system toxicity. In patients with impaired hepatic function, the half-life and hence duration of action of procaine are prolonged. In patients with seizure disorders particular vigilance should be maintained for any manifestations of central nervous symptoms.

Interactions with other agents:

The antibacterial efficacy of concurrent sulphonamide therapy is reduced by the procaine metabolite p-aminobenzoic acid. Concurrent therapy with cholinesterase inhibitors may lead to accumulation of procaine due to interference with procaine catabolism. Simultaneous administration of non-depolarising muscle relaxants will prolong the duration of action of procaine.

Dosage:

In general, 3-1 times weekly 1 ampoule i.m., s.c., i.d. (at focal disorders, acupuncture points, or on a segmental basis). Do not perform i.v. injection of this medication.

Package sizes:

Packs containing 5, 10, 50 and 100 ampoules of 2.2 ml.

Pharmacological and clinical notes

Viscum album (mistletoe)

Attacks of vertigo, headache, especially in the forehead, constitutional hypertonia, arteriosclerosis, pruritus sine materia,

precancerous state and neoplasia. Ginseng (ginseng root)

Conditions of exhaustion of all kinds. Artemisia abrotanum (southernwood)

Emaciation in spite of a good appetite, status lymphaticus, exudative diathesis. China/Cinchona (Peruvian bark))

Remedy for debility, retarded convalescence, anaemia, sensitivity to cold. Berberis vulgaris (berberis)

Arthritic and rheumatic diseases, diseases of the kidneys and bladder. Procainum hydrochloricum (procaine hydrochloride)

Geriatric remedy, arteriosclerosis, peripheral circulatory disorders, neuralgia.

Based on the individual homoeopathic constituents of Procainum compositum, therapeutical possibilities result for the revitalization of cellular phases and the support of the defensive system.

Since the defensive system, especially in cellular phases and in neoplasia, becomes increasingly strained and finally exhausted, Procainum compositum is indicated not only as a geriatric remedy but also for revitalisation in cellular phases of all kinds, particular for precancerous state, but also for neoplasia which has already appeared.

Procainum compositum is especially indicated, including in general toxin levels and for high homotoxin levels, e.g. reaction phasese such as influenza (with Ubichinon compositum ampoules, Gripp-Heel, Echinacea compositum S), for total catarrhal aphonia (with Euphorbium compositum S, Mucosa compositum, Echinacea compositum S and possibly Ubichinon compositum ampoules) as well as for neuralgia and in areas of neural disturbance.

In neoplasia, the application of Glyoxal compositum is beneficial (usually injected very rarely or once only) in order to release the decomposition and depolymerisation processes through the immune defences (W.F. Koch), possibly with the addition of cAMP D 30 and Pulsatilla compositum; Thalamus compositum once weekly (influence of the faulty neural control) as mixed injection with Procainum compositum. In neoplasia, further alternating injections with Viscum compositum (medium, forte), Echinacea compositum forte S, etc.

The dosage is adjusted according to the clinícal picture and the stage of the illness: in general, 1 ampoule i.m., s.c. or i.d. 2-3 times weekly; upon improvement, possibly continuing only once weekly. The preparation can also be used safely mixed with homoeopathic remedies of all kinds. Procainum compositum + cAMP D30 has an excellent action.