Category: Publications

Parent category to all problems relating to the physical aspect of the body

Dysbiosis: The missing link between health and disease Lennart Cedgard M.D.
Dysbiosis: the missing link

This booklet will give information about intestinal dysbiosis. This condition is characterised by an imbalanced intestinal bacterial flora. It will explain the relationships between food and lifestyle and its impact on health and diseases. In the intestine, micro-organisms influence our body functions in many different aspects, i.e., biochemically and immunologically. It is most important to treat the microflora in an enlightened probiotic direction.

These probiotics, often some sort of lactic acid producing cultures, are able together with the host’s own flora, to deal with disturbances due to inadequate food, stress and strain, environmental toxins and different medical drugs such as antibiotics, contraceptives, painkillers etc.

The intestinal flora influence the immune system and regulate the body’s ability to cleanse itself of waste products, i.e., detoxification. A harmonised and balanced flora will contribute to a better absorption of nutrients, i.e., minerals, trace elements, vitamins and amino acids.

Intestinal Dysbiosis

What is dysbiosis?

Dys- means faulty and -bios is life and growth. This implies faulty life. In biological terms, the phrase intestinal dysbiosis is used for an unbalanced bacterial flora in the intestine. You could say the microflora is dysbiotic. Normally, it is understood this condition includes harmful metabolic activity of the flora.

How does dysbiosis develop?

There are many factors that influence what type of bacteria or micro-organisms will grow or colonise in the gastrointestinal channel. In the mouth, there are already quite a number of bacteria. Many of them come from the intake of food. In the ventricle, the amount will be reduced. In the small intestine, the numbers of bacterial cells increase from the beginning towards the end (i.e., E5 to E9–10/g content). You’ll find the highest amount of bacteria in the colon (i.e., E10–11/g content). Stress, food, medical drugs, environmental toxic loading, and climate are all factors that stimulate or inhibit different types of micro-organisms. A poorly balanced diet will create a dysbiosis.

Different life situations with psychic stress or disharmony are also very influential in creating a dysbiosis. A great number of medical drugs inhibit the beneficial flora from acting normally. Environmental toxins can also provoke an intestinal dysbiosis. Food supplements taken inadequately will disturb the important balance. It should be noted that the climate supports a variety of different bacterial cultures. This is often experienced when travelling, i.e., tourist diarrhoea.

What conditions or diseases depend on dysbiosis?

Dysbiosis will often show as functional disturbances in the ventricle or the intestine. Symptoms such as dyspepsia, constipation or loose stools are conditions that will later develop into gastritis and chronic inflammation in the intestine. Ulcers in the ventricle or the intestine could result if the dysbiosis is not properly regulated. Gallbladder problems and obstipation or diarrhoea are often related to intestinal dysbiosis. Dysbiosis can also manifest in dysfunction of the immune system, i.e., food intolerance. Atopies or allergies, i.e., eczema and urticaria, are of similar origin. Chronic inflammatory diseases, i.e., arthritis, are also developed in the context of dysbiosis. Certain types of migraine, where food and diet are significant in the outbreak, could be a symptom of intestinal dysbiosis.

How will dysbiosis be inhibited?

Through the stimulation of beneficial bacteria in the intestine, the degree of dysbiosis will be reduced. Optimising the food intake and avoiding detrimental stress, mental and physical welfare can be disrupted by harmful medical drugs, environmental toxins and micro-organisms. There are not many of us that can live in total harmony. This would be an utopia. To be successful in this, you must learn what is beneficial and what is harmful for the intestinal flora in general and in each case.

Eubiosis and Probiosis

What is probiotics?

Lactic acid bacterial cultures, so-called probiotics, stimulate colonization of the so-called human autochthonous flora in a beneficial direction. Probios means for life. A condition without any dysbiosis is called eubiosis. It is more likely to be an utopia. Reducing the degree of dysbiosis is called probiosis. That is why the cultures are called probiotics.

As a therapist, you of course advise your patient to optimise all the factors mentioned above. A well-balanced diet and life pattern is the best insurance for being healthy. In most cases, probiotics could be an important, if not crucial, complement.

Bifidobacterias and Bacteroides

What bacteria are there in the stomach and the intestine?

When fasting, you only find small quantities in the stomach. Together with the intake of food, the amount of bacteria will increase to E5 cfu/ml liquid. There often are streptococci, bifidobacteria, enterobacteria and bacteroides—some of them emanating from the mouth and the food itself. These will be reduced when the stomach starts producing acid and the pH is reduced. Further down in the small intestine, the number of cells increases again; E5–7 cfu/ml content.

In the colon, the numbers increase dramatically. The two dominating types of cultures are bacteroides and bifidobacteria. There are about E10–11 cfu/g faeces. The weight is 0.5–1 kg! The total amount is E14. This is related to the total amount of human body cells, which is E13. This implies there are 10-fold more micro-organisms than body cells! This is of great importance, especially when referring to the immune system. The Peyer’s patches in the small intestine play the most important role in the control and balance of the immune system and its relation to the microflora. There is a microeco-intesto-immuno-endocrino-neuro-psycho linkage.
This explains many of the syndromes described, where you find both physical and psychiatric disorders closely related to each other.

Fermentation and Putrefaction

Simplified, you could separate the bifidobacteria as the good ones and the bacteroides as the evil ones. Bifidobacteria split the food by fermentation. Lactic acid, acetic acid and butyric acid are produced. These will create a more acidic environment in the intestine.

The bacteroides will digest the food by putrefaction. It will then produce nitrogen waste products. These are harmful for the human body, and they will be absorbed in the intestine, reaching all the different body tissues.

Streptococci, enterococci, and enterobacteria (i.e., colibacteria) are found in minor quantities. In adolescents, the quantity of bifidobacteria is lower.
This is shown on page nine.

What sort of diet promotes a healthy flora?

Food rich in complex carbohydrates with a low glycemic index. These are broken down relatively slowly and will provide you with a steady blood sugar level. Vegetables of different types, rice, and pasta are adequate roughage.

A high intake of protein and animal saturated fatty acids stimulates the activity of bacteroides towards putrefaction. In western society, we strain our bodies with the intake of too much protein and saturated fatty acids. The WHO standard protein requirement is approximately 0.8 g/day/kg body weight.

An intake of high amounts of fibre improves the motility of the intestine. This promotes the bifidobacteria. A vegetarian diet contains many different food fibres such as cellulose, hemicellulose, and pectin. An intake of fibres should always be followed by intake of water.
The term “throw water” is adequate. It indicates enough hydration.

The Immune System and Lymphoid Tissue

The intestinal flora communicate with the immune system through the so-called lymphoid tissue. This tissue is found in crypts in the small intestinal mucosa. It is called the Peyer’s plaque. Deeper in the intestinal tissue there is the lamina propria with lymphoid tissue. All this is connected together with lymphatic vessels directed towards the lymph nodes. These are located in the mesenteric fibrous tissue that lines the small intestine. This is related to the other parts of the immune system. The intestinal-related immune system is in this manner able to read and translate or react on the biochemical activities in the intestine.

The immune system is stimulated or inhibited by different bacterial cultures or food items. Dysbiosis creates a disharmony in this complicated relationship. The human being is born with a genetic memory that decides what sort of food will be accepted or not. If we introduce new unknown food items into the body, there is a risk that the immune system will react against them.

Certain probiotics can induce an immunogen effect. It means B- and T-lymphocytes are stimulated and the concentration of immunoglobulins is increased. Probiotics are transitory. They do not normally colonise on the intestinal mucosa.

Nitrogen Waste Products

What happens in the intestine biochemically and immunologically during probiotic therapy?

Those enzymes the body itself uses for digesting food are influenced directly or indirectly by all the micro-organisms there are in the stomach and the intestine. This is called enzyme induction. Certain compounds that are produced in the digestion of food are toxic and cause harm in different tissues. When there is intestinal dysbiosis, these compounds are found in high quantities.

Probiotics will reduce the dysbiosis and thereby the accumulation of toxic waste products. When protein is digested through the action of these harmful intestinal micro-organisms, directly or indirectly, a variety of nitrogen waste products—such as ammonia, urea, indols, phenols, nitrites, and nitrosamines—will be produced.

These toxic items could, in a later sequence, influence the outcome of different unhealthy conditions, i.e., chronic diseases where the immune system is seriously involved. They also promote the development of polyarthritis and skin diseases.

Normally, the liver is able to detoxify all these toxins. However, if the load is heavy and prolonged, the liver will not be able to cleanse completely.

Detoxification and Retoxification

Certain beneficial bacteria are able to neutralise toxic metabolites. This is called detoxification. The opposite is retoxification. It is the conversion of non-harmful products to harmful ones. Probiotics reduce the pH in the intestine, causing the activity of the coliform putrefactive bacteria, such as bacteroides and clostridia, to be inhibited. The production of their metabolites will then be reduced. Additionally, the absorption of these is impaired, resulting in them being excreted in the faeces.

Conjugation and Deconjugation

One of the methods the liver uses to neutralise toxins is by conjugating them with glucuronic acid, thereby creating glucuronides. This process is called conjugation. When these are excreted from the gallbladder out into the intestine, it is given the capability to get rid of toxins.

When there is a dysbiotic condition in the intestine, certain bacteria improve their ability to digest these conjugates. This is called deconjugation. The toxins are reabsorbed into the blood. The result is retoxification.

Some of the enzymes that deconjugate and retoxify toxic waste products are:
- Beta-glucuronidase
- Azoreductase
- Nitroreductase
The outcome of their action is an increased accumulation of toxic metabolites. By probiosis, this will be reduced.

Glycosides from different green plants, such as rutin, may be converted by the action of Streptococcus faecium to quercetin. This molecule is mutagenous. It will cause injuries to the body cell’s genetic code. This can develop into malignant conditions, i.e., cancer.

Streptococcus faecalis is responsible for another sort of retoxification. It converts the amino acid tyrosine to tyrosamine. An increased amount of tyrosamine is thought to trigger attacks of migraine. In a later phase, this amine is converted to phenol, which is mutagenous.

Oestrogen

Bile acids, cholesterol, and a variety of sex hormones are exposed by the same mechanisms, i.e., conjugation and deconjugation. They are excreted by the bile into the intestine. Further down in the intestinal channel, they are reabsorbed. A certain amount is lost in the faeces. A loss of volatile bile acids and, to a certain degree, cholesterol are lost in the same manner, which could be favourable.

It is not desirable for the sex hormones to be lost in the faeces. Both female and male hormones can be lost in this manner. This happens when there is an intestinal dysbiosis. A reduced concentration of oestrogen can cause:
- Bleeding disturbances
- Increased sensitivity to genital infections (i.e., vaginitis)
- Bladder infections (i.e., cystitis)
- Impaired fertility
- Osteoporosis with pain syndrome
You may experience similar mechanisms when taking contraceptives and antibiotics at the same time.

Endotoxins

When there is dysbiosis, certain bacteria (i.e., clostridia) produce endotoxins, which will influence the immune system. A great number of chronic inflammatory diseases are related to dysbiosis. These immune-related diseases will appear in various soft tissues such as the skin, joints, urinary system, intestine, eyes, glands, etc.

Carcinogens and Insulin

Deconjugated bile acids and cholesterol are to be converted further in a later phase. The harmful bacteria stimulate the production of an increased amount of volatile secondary bile acids and coprostanol, which is a digested product of cholesterol. These are carcinogenic, including the above-mentioned enzymes and the nitrosamines. They promote the initiation of different types of cancer, e.g., breast cancer.

An unbalanced intake of short and rapidly digested carbohydrates (i.e., glucose) intensifies the development of dysbiosis. Note the glycaemic index of different food items and their bioavailability.

There is an insulin-like substance produced by E. coli bacteria. It is a sort of analogue. This substance is thought to be absorbed into the blood and situate itself on the receptors where human insulin is normally positioned. Thereby, it will inhibit the action of insulin.

In diabetic patients, you often find dysbiotic conditions.

Vitamins and Analogues

The bacterial flora in the colon produce a variety of vitamins. The absorption of these is relatively poor. It is impossible to estimate how important this vitamin production is. All of the B vitamins and the K vitamin are produced. The latter is essential for coagulation ability. Most of our need is absorbed in the small intestine.

What is of more interest is that bacteria consume vitamins for their own survival. When there is dysbiosis, this consumption is increased in the lower part of the small intestine. Vitamin B12 will in this manner be consumed. Depressed levels of vitamin B12 are seen amongst older people; compare this with the reduced action of the bifidobacteria.

It is known that bacteria are able to produce so-called vitamin analogues. These analogues compete with the real vitamins. They act as ghosts and are believed to cause functional conditions of insufficiency. The traditional tests on vitamin B12 are inadequate and insufficient. The level of homocystein gives a better understanding of the vitamin condition. It could also in some cases function as an indirect parameter estimating dysbiosis.

As mentioned above, the autochthonous flora create a barrier and protection against hostile and not welcoming guests. The majority of the pathogen or disease-provoking bacteria are sensitive to competition from the natural flora.

When there is dysbiosis, their establishment will be facilitated. Probiotics reduce the pH in the intestine by 1–2 units. This will aggravate the establishment of, e.g., salmonella, cholera, etc.

The bifidobacteria defend their territory by producing different organic acids, i.e., acetic acid, lactic acid, and special natural antibiotics.

Certain Conditions When Probiotics Are of Importance

Below is a variety of conditions more or less related to intestinal dysbiosis.
The dysbiotic condition is directly or indirectly related to symptoms.
- Gastritis and ulcer
- Gallbladder dysfunction and liver diseases
- Constipation or irritable colon
- Obstipation or diarrhoea
- Dyspepsia
- Migraine; conversion of tyrosine to tyrosamine
- Atopies (e.g., eczema, hay fever, urticaria, asthma)
- Food intolerance (e.g., gluten intolerance)
- Chronic inflammatory or autoimmune diseases (e.g., rheumatism, SLE, fibromyalgia, psoriasis, colitis ulcerosa, Crohn’s disease)
- Infections in the urinary system
- Mycosis (e.g., Candida albicans)
- Exposure to radiation, cortisone, antibiotics, contraceptives
- Conditions with impaired immune defence (e.g., malignant diseases such as leukaemias)
- Insufficiency of vitamins or minerals
- Stress
- Skin diseases (e.g., acne, herpes)
- Hormonal dysfunction (e.g., bleedings, menstruation dysfunction, infertility, osteoporosis)
- Metabolic syndrome and diabetes
- Chronic fatigue syndrome
These conditions illustrate when probiotics may be particularly beneficial, due to their potential role in restoring balance to the intestinal flora.
November 7, 2025

Detoxification and Drainage Eliminating toxins from the body By Bruce H. Shelton, MD, MD(h), DiHom

There are very few patients who don’t need detoxification and drainage intervention at all. Furthermore, each patient’s status is unique, so in designing a treatment plan, it is important to strike a balance between the patient’s previous exposure (toxic load) and the organism’s ability to detoxify (regulation ability).

For this purpose, patients are generally divided into two groups. Group 1 includes patients with mild to moderate toxicity. In general, these are patients with mild symptoms and exposure. They elect to do a general cleansing or have milder diseases such as headaches, acne, etc. Group 2 includes patients with severe toxicity (known exposure) as well as patients with severe diseases such as cancer, autoimmune diseases, etc. These patients’ regulation ability is reduced. Group 2 also includes former drug addicts as well as patients who have received chemotherapy.

Due to their advanced toxicity, Group 2 patients need advanced supportive detoxification that prepares the organs of detoxification and elimination for the drainage phase (accomplished primarily through Lymphomyosot, a component of the Detox-Kit). The advanced organ support is thus more organotropic in character, whereas the basic detoxification and drainage is more functiotropic. In general, advanced organ support is administered for six weeks, followed by use of the Detox-Kit. In most cases, tissues will still need to be drained of residual toxins, so the use of Lymphomyosot alone is advised for several months longer (for protocols, see BT Winter 2007).

Special case 1:

Patients with inflammatory skin disease, such as eczema or psoriasis. The skin, classically called the “mirror of the soul,” is also a mirror of the liver and the gut. In cases of skin disease, it is essential to remember that the P450-containing system in the skin is the same as that in the liver and in the gut. Psoriasis patients in particular need bowel cleansing, which should be part of the initial advanced organ support. Thus Mucosa compositum and Cutis Compositum play a special role in these patients, although functiotropic medications such as Nux vomica-Homaccord, Berberis-Homaccord, and Lymphomyosot, along with Hepeel, are the mainstays in the treatment of skin disease. Patients with inflammatory skin disease are at high risk of flare-ups if toxin drainage is initiated before the liver and gut are ready to cope with the load. These patients need to be treated with care even though they may not seem very ill. In some cases, flare-ups will simply mean that patients need higher doses of cortisone, but in other cases hospitalization may become necessary if skin sloughing is severe.

Patients with eczema are in a Th2 rigidity state, so they should first undergo several weeks of initial immunomodulation to get the disease under control, followed by advanced organ support, before the drainage period is initiated. Engystol is the medication of choice together with the appropriate suis-organ preparation, in this case Cutis compositum. By contrast, patients with psoriasis are in a Th1 state, so they should be treated with Traumeel oral ampoules and Cutis compositum. In both cases, it is preferable to add the catalysts during the drainage phase rather than during advanced organ support (see protocol in Table 1).

Table 1: Protocol for inflammatory skin disease

Disease-Specific Treatment

For Th1 rigidity: Traumeel and Cutis compositum
For Th2 rigidity: Engystol and Cutis compositum
Schwef-Heel

Weeks 1–4 (or even longer in severe cases)

Organ/System	Treatment
Liver	—
Urinary tract/Kidney	—
Lymph	—
Skin	Cutis compositum
Gut	Mucosa compositum
Connective tissue	—

Note:
Due to the high incidence of leaky gut in inflammatory skin diseases, initial treatment of the gut and immune system is paramount. The suis organs induce Th3 cells and thus immunotolerance to the corresponding organs.

Dosage:

Ampoules: In general, 3–1 times weekly, 1 ampoule i.m., s.c., i.d.
Drops: In general, 10 drops 3 times daily

Advanced Organ Support

Duration: 6 weeks

Organ/System	Primary Treatment	Alternative Products
Liver	Hepar compositum	Hepeel
Urinary tract/Kidney	Solidago compositum	Reneel
Lymph	—	Galium-Heel / Lymphomyosot
Skin	Cutis compositum	Schwef-Heel
Gut	Mucosa compositum	Nux vomica-Homaccord
Connective tissue	Thyreoidea compositum	Pulsatilla compositum

Basic Detoxification and Drainage

Organ/System	Detox Treatment	Cellular Detox (Add)
Liver	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Urinary tract/Kidney	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Lymph	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Skin	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Gut	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Connective tissue	Detox-Kit	Coenzyme compositum / Ubichinon compositum

Note:
Because Schwef-Heel is a potency chord, it does not cause aggravation to the extent classically ascribed to sulfur-containing medications. Adjuvant use of probiotics throughout the treatment should be considered.

Dosage:

Ampoules: In general, 3–1 times weekly, 1 ampoule i.m., s.c., i.d.
Drops: In general, 10 drops 3 times daily

Practical Protocols

Chronic fatigue syndrome is a complex and highly debilitating disorder characterized by chronic mental and physical exhaustion. It occurs more often, but not exclusively, in women.

Special case 2: Patients with chronic fatigue syndrome.

All patients with chronic fatigue syndrome have some form of toxicity. Some of these patients present primarily with symptoms of intoxication and have a history of toxic exposure, often temporally related to the onset of the syndrome.

Due to general immune imbalance (Th2 rigidity) and mitochondrial impairment in these patients, advanced organ support is essential, but even before that, support for the mucous membranes, the immune system, and the neuroendocrine system is helpful. This is best done with a combination of Mucosa compositum and Tonsilla compositum. After two weeks, advanced organ support can begin, followed by the drainage phase. If relapse occurs during the drainage phase, advanced organ support should be resumed for at least another six weeks (see protocol in Table 2).

Table 2: Protocol for chronic fatigue syndrome

Disease-Specific Treatment: Aletris-Heel

Followed by detoxification therapy

Weeks 1–2

Organ/System	Treatment
Liver	—
Urinary tract/Kidney	—
Lymph	Tonsilla compositum
Gut	Mucosa compositum
Connective tissue	—

Weeks 3–8: Advanced Organ Support

Organ/System	Primary Treatment	Alternative Products
Liver	Hepar compositum	Hepeel
Urinary tract/Kidney	Solidago compositum	Reneel
Lymph	Tonsilla compositum	Galium-Heel
Gut	Mucosa compositum	Nux vomica-Homaccord
Connective tissue	Thyreoidea compositum	Pulsatilla compositum

Weeks 9–20: Basic Detoxification and Drainage

Organ/System	Detox Treatment	Cellular Detox (Add)
Liver	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Urinary tract/Kidney	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Lymph	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Gut	Detox-Kit	Coenzyme compositum / Ubichinon compositum
Connective tissue	Detox-Kit	Coenzyme compositum / Ubichinon compositum

Note:
These patients need very gradual treatment. Because they often have multiple chemical sensitivities, it is advisable to first restore the integrity of the gut lining while administering Tonsilla compositum to support the adrenals and the hypothalamus. This also supports the immune system.

Dosage:

Ampoules: In general, 3–1 times weekly, 1 ampoule i.m., s.c., i.d.
Drops: In general, 10 drops 3 times daily

November 7, 2025

DENTISTRY AND HOMEOPATHY: AN OVERVIEW Richard D. Fischer, D.D.S.

INTRODUCTION

The dental profession is becoming increasingly aware of the indivisibility of dental health and overall health. The teeth, the tongue, the gingiva, the lips, the salivary glands, etc. are all integrated with the rest of the body via the nerves, the blood and lymphatic circulations, glandular secretions, acupuncture meridians, the connecting bones and joints and by the digestive tube which extends from the mouth to the anus.

Because of the mechanical nature of most dental therapeutic procedures it may occasionally be convenient to forget that the mouth we are treating is connected to a vital, breathing, thinking, feeling human being. Yet the profound interrelationships between the mouth and the rest of the body have been recognized in the scientific literature of the West for several decades and by the Chinese for some fifty centuries.

When treating someone with an oral health problem, often the cause is found locally—such as a broken tooth due to trauma, a lost filling, or a sore spot from an ill-fitting denture. But more frequently the cause is found outside the mouth. This is particularly true of the more chronic oral maladies, such as periodontal disease, temporomandibular joint (TMJ) disorders, oral cancers, bruxism, bad breath, herpes simplex, tooth decay and, more recently, AIDS. Other common examples of this remote causation of oral pathology include the severe alveolar bone resorption found around the roots of the teeth in the diabetic patient,⁴ and the gross proliferation of fibrous tissue of the gingiva in the epileptic patient receiving Dilantin therapy.⁵ Even the American Dental Association now recognizes this systemic causation of periodontal disease.³ The dentist is sought out for evaluation and treatment of these oral symptoms—despite the fact that these oral symptoms are merely a localized manifestation of a more systemic disturbance.

Perhaps less widely appreciated but, I maintain, more frequent in occurrence are those systemic maladies which result from oral sources—as has been elaborately described and documented by Dr. Rheinhold Voll,⁴ and others.⁵ ⁶ Typical examples include the constipation of the TMJ patient due to his impaired chewing ability, or the migraine headaches of a mercury-hypersensitive physician provoked by a mouthful of amalgam (50% Hg) fillings, or the abdominal rash of the nickel-hypersensitive woman elicited by placing a nickel crown on her tooth. In these cases, ironically, the patients traditionally must seek the treatment of a physician (rather than the dentist) because of the systemic nature of the symptoms—despite their oral origins.

Consider that only a few decades ago it was fairly common “medical” treatment for rheumatoid arthritis to extract all the patient’s teeth—frequently with great success. One cannot soberly ignore the fact that what we do in our dental treatment can profoundly affect that individual’s systemic health and vice versa.

Once this concept is embraced, then the role of homeopathy in dentistry is much easier to appreciate. We will look at both acute and chronic dental prescribing, in this paper, and then explore the three basic constitutional types.

ACUTE DENTAL PRESCRIBING

Over the years I have found that a handful of remedies can handle the majority of the acute dental emergencies with which I have been faced in my practice. These first-aid remedies can help alleviate the pain or discomfort of dental emergencies, at least temporarily, until proper dental care measures can be received. I must emphasize, however, that the remedial measures proposed herein are not intended to replace good dental care, but rather to serve as a safe and effective complement to good dental care. (The potencies mentioned below are only suggestions. These are the ones I have used in my practice. A 30C should work as well as a 30X. As in all homeopathic prescribing, the remedy selection is more important than the potency. In other words, if the case calls for Belladonna 30X and all you have is Belladonna 6C, use it!)

Abscesses

Belladonna. Early dental abscesses, accompanied by redness and throbbing which is aggravated by the slightest touch (30X every 30–60 minutes).
Hepar sulphuris calcareum. Where the abscess is accompanied by pus formation, increased salivation, and where the gums are sore to the touch and bleed easily. Repeated doses of 6X will encourage pus discharge, while higher potencies (30X–200, two or three times daily) will help abort pus formation.
Silicea. Once pus is draining, Silicea 6X a few times daily will hasten the discharge.
Myristica. Where the abscess is swollen and accompanied by numbness of the area. Especially suited to the wisdom teeth. (6X)
Calendula. Dilute the tincture 1 part to 20 parts of water. Use as a gentle but effective disinfectant mouth rinse. This may be used several times daily (with any of the above remedies or by itself) or may be alternated with warm salt water rinses.

Apprehension (anticipation of the dental visit)

Gelsemium. Fear accompanied by “weak knees,” diarrhea, and drowsy behavior. 30X to be taken the night before, the morning of and ½ to 1 hour before the dental visit.
Aconite. When the fear is accompanied by great panic (sudden onset) as well as physical and emotional restlessness (e.g., much fidgeting). 30X taken as above.
Coffea cruda. 30X is helpful when the anxiety is accompanied by intolerance to noise or music.
Chamomilla. This is not for apprehension, per se, but may greatly help those individuals with lowered pain thresholds. Take three doses of 30X over several hours prior to the dental visit.

Bleeding

Almost all post-surgical bleeding is well controlled by pressing a moist gauze pad or moist tea bag over the bleeding area. However, when this alone does not control the bleeding:

Phosphorus. 6X to 200X every 10 to 30 minutes until the bleeding stops.
Arnica. If bleeding is accompanied by bruised soreness. 30X every 10 to 30 minutes until bleeding is controlled.

“Dry Socket”

Belladonna. 30X every 30 to 60 minutes if accompanied by a throbbing pain.
Ruta graveolens. 6X for any surgery or other injuries to the jaw or other facial bones.
Calendula. As prepared above is a good healing rinse.

Teething

Chamomilla 30X every 30–60 minutes when the teething child is whiney, restless, and wants to be held and pampered. This is a great remedy for delayed and difficult teething.

Toothaches

Belladonna. 30X every 30 to 60 minutes when the toothache throbs and is worse from touch or motion (chewing).
Magnesia phosphorica. 30X when the toothache is worse from cold and better from warmth.
Coffea cruda. 30X when the toothache is worse from heat and relieved by holding ice in the mouth.
Chamomilla. 30X when the toothache is worse from any warmth (i.e. if anything warm is taken in the mouth or even upon entering a warm room), but not better with cold. The pain is intolerable and makes the patient peevish.

Dental Trauma (or Post Operative) Remedies

Arnica. 30X for injuries resulting in bruises or fractures; for sore spots from an ill-fitting denture; following the placement of a very deep filling. (Many patients find Arnica helpful when taken before a dental visit where discomfort is anticipated)
Hypericum. 30X where nerves have been injured—such as a broken tooth where the nerve has been exposed, and accompanied by excessive pain.
Ledum. 30X for puncture wounds, such as the soreness resulting from a dental injection.
Staphysagria. 30X for incision type wounds after soft tissue surgery—as with extractions of difficult impacted wisdom teeth or periodontal (gum) surgery.
Chamomilla. Helps expedite the wearing off of the numbness following the completion of the dental procedure. 30X every 20 to 30 minutes. Works beautifully!
Magnesia phosphorica. 30X for stiff, sore jaws following a prolonged dental visit with the mouth wide open where the muscles are cramped and feel better with warmth. If they don’t feel better with warmth, try Arnica 30X instead.

CHRONIC DENTAL PRESCRIBING

Now that we have looked at some of the homeopathic treatments for a few of the more common acute dental problems, I would like to explore the role of homeopathy in the treatment of chronic dental or oro-facial complaints. To evaluate and treat someone for a chronic dental problem (i.e. periodontal disease, chronic TMJ disorders, bruxism, or rampant tooth decay) one must exercise the same deliberation as when treating any other chronic conditions—that is, a thorough history and examination must be done. To give adequate scope to the ongoing disease process and its various causes, one must include not only the dental manifestations, but all levels of the patient’s symptoms (physical, mental, emotional, and spiritual) in the evaluation. “How can a dentist evaluate one’s mental condition?” you ask. Remember, the repertories and materia medicas are written (gratefully) in plain English—not in “medicalese.” One needn’t be skilled in abnormal psychology to see that a patient is frightened, cheerful, or angry. One need only observe and listen!

Dentists have particular expertise in evaluating a person’s oro-facial signs and symptoms (which, incidentally, comprise a very significant portion of Kent’s Repertory), and this is the focus of our therapy. However we are sometimes criticized for “practicing medicine without a license” because through appropriate “dental” therapy the patient’s “medical” condition improves. The reader will understand from the initial discussion in this paper the error of such thinking. Furthermore, homeopathic remedies (like allopathic drugs) are not organ specific. They affect the entire person. Thus, when you visit a dentist complaining of a swollen jaw and he gives penicillin for the infected wisdom tooth, doesn’t your infected hangnail respond to the medicine as well? Likewise, even though it may not be our intention to witness a cure of sciatica or dyspepsia with correct dental treatment, such things do happen and, as with the infected hangnail, this obviously does not imply that we are practicing medicine. Remember, it is the individual’s vital force, not the prescriber’s intentions, that directs the evolution of cure, as the case below well illustrates.

Over the past twelve years a large portion of my practice has dealt with the care and treatment of people suffering from disorders of the temporomandibular joint (TM joint or jaw joint). This paired joint connects the lower jaw to the skull and lies just in front of the ears. Because disorders of this joint cause such profound and diverse sequelae in the patient’s overall health, they serve as a good vehicle to illustrate the indivisibility of oral and systemic health. The various signs and symptoms of TM joint disorders fully permeate one fourth of the pages of Kent’s Repertory. They include headache, earaches, grinding and popping noises in the joint, vertigo, pains in the neck, shoulders, and back, indigestion, poor balance, unstable posture, and many others.

CASE HISTORY

On July 25, 1983 a 20-year-old woman presented with a constant headache which had begun 12 months before. The headache was worse upon awakening in the morning and began one month after leaving home to attend college. She had difficulty eating because chewing caused pains in the right temple. She also suffered from chronic constipation, insomnia, and fatigue. She appeared pale, unsmiling, and listless and she had not had her menses for seven months. Prior treatments had been of little help and included therapy by neurologists, gynecologists, a psychiatrist, an allergist, internist, nutritionists, acupuncturist, chiropractors, dentists, a cranial osteopath, and a neurolinguistic programmer. She had a history of other head injuries. She was given Arnica in high attenuation.

Two months later she reported no significant change in her health. She was fitted with an orthopedic appliance and put on an exercise program to help alleviate her jaw muscle tension. Within days she began to sleep better, but over the next few months the headaches were still constant, although diminished. She still had no menses, was thirstless and still constipated. She was given Natrum muriaticum 1M.

Natrum muriaticum has headaches, worse in the morning as part of the remedy picture. Also included are a great variety of menstrual complaints, constipation, difficulty sleeping, and emaciation. It is the chronic of Ignatia, often, as Boericke says, “having psychic causes of disease”* (i.e. leaving home).

When she returned a month later, her appearance had dramatically improved. Her face was more animated, her dress more colorful, and her voice more vibrant. She was sleeping well and her head and jaw pains had markedly lessened. Her cranial osteopath reported the first profound improvement in her cranial mechanism since he had begun treating her. Several days after the remedy was given she had her first menses in almost a year.

THREE CONSTITUTIONAL TYPES

In taking a case of a chronic dental patient one can garner a great deal of information as to the patient’s constitutional type by examining his or her oral and cranial structures. Here I must define “constitutional” in its narrowest sense, based on the theory of constitutional typing by Nebel and Vannier, also referred to by Professor Eizayaga, M.D., as the “genotypical” constitutional type. That is, the constitution is the least changeable aspect of the person’s totality; it is based largely on the structure and composition of one’s tissues and skeletal framework, and therefore is immutable and established long before birth.

Our skeletal and dental structures are composed of three calcium salts (or Calcareas): the carbonate, phosphate, and fluoride. Each of these salts impregnates our teeth and bones and thereby imparts to us distinctly different anatomical characteristics, different metabolic types, as well as different disease propensities. Accordingly, everyone belongs to one of these three constitutional types: Calcarea carbonica, Calcarea phosphorica, or Calcarea fluorica, depending upon which salt predominates in our makeup. Furthermore, to each of these constitutional types belong a group of remedies or “phenotypical” constitutional types (Eizayaga). While it is common to see individuals who exhibit combinations of these three constitutional types (especially mixtures of the phosphor-fluor and fluoric-mixed type), one type will always predominate.

As we shall see, nowhere are the anatomical differences among the Calcareas more dramatically illustrated than in the dental apparatus. Thus the dentist has a unique vantage for assessing a patient’s constitutional type, and therefore can gain much insight into that individual’s therapeutical needs. The information I am presenting here is largely lacking in the homeopathic Materia Medicas and I am therefore greatly indebted to M. Tetau, M.D., F. Fuller Royal, M.D., and E. Illovici, M.D., for their writings which helped consolidate the constitutional pictures you are about to meet.

Calcarea Carbonica

The carbonica has broad shoulders, a broad forehead and large jaws. The teeth are very white and well aligned but are slow to erupt with difficult teething. The fontanelles of his very large skull are slow to close and his head perspires easily. His tongue is dry, he does not like to talk, and his teeth cannot endure any coldness—even cold air!

The carbonica resembles the oyster shell from which the remedy is made, that is, he is resistant to change—“a victim of inertia.” Yet, while slow to begin a project, he will, once started, continually plod ahead until the job is completed. While not terribly imaginative, he is logical and is good with mathematics (many mathematicians and accountants are carbonicas).

His long bones and spine are curved, and his bones, joints, and muscles are as rigid and inflexible as his opinions. He tends to develop hypertension, hypothyroidism, obesity, and autointoxication due to his failure to remove toxins adequately from his body. The child exhibits delayed puberty and is frequently troubled by bedwetting. He is chubby, his complexion has a chalky tint, and he is prone to digestive complaints.

Major remedies related to the Calcarea Carbonica type aid in the elimination of the body’s toxins: Sulphur, Hepar sulph., Graphites, Silicea, Carb. veg., and Lycopodium.

Calcarea Phosphorica

The phosphoricum type is mentally precocious and develops early. He is tall with long arms and legs and his back is stooped. The skull is long (front to back) and narrow, as are the jaws. The forehead is elevated and the nose strong. The teeth are oval and have a yellow cast to them. The palate is narrow with a gothic (high) vault.

He is very imaginative and artistic and does not tolerate manual labor or any regularity in his life style. Because he cannot stay with any task for very long, he seldom masters anything—despite being a perfectionist at heart.

He has long eyelashes, his hair is fine, and his skin delicate. When he perspires, he does so all over. He tends toward hyperthyroidism, palpitations, and tuberculosis.

Major remedies related to the phosphoricum constitutional type are Natrum mur., Ferrum, Kali carb., Iodium, Arsenicum album, Phosphorus, and Stannum.

Calcarea Fluoricum

The fluoricum constitution is the picture of instability both mentally and physically. The bones are deformed and the muscles and ligaments are very lax, producing an “S”-shaped posture. The arms hyperextend at the elbows. The dental arch and alignment of the teeth are irregular. The upper jaw protrudes, the feet are abnormally small and the hair is hard and brittle.

He dislikes exercise and has little physical endurance. He cannot concentrate on anything for long periods of time and seldom perspires at all. His temperament is unstable, he has little control over his reactions, and will say whatever is on his mind. All of his symptoms are worse at night but he feels better in the mountains. He tends toward arteriosclerosis, arthritis, and hypertension.

The major remedies that relate to the fluoricum constitutional type are: Mercurius, Aurum metallicum, Argentum nitricum, Kali bichromicum, Platina, Nitricum acidum, Baryta carbonica, and Syphilinum.

The following chart summarizes the characteristics of the three calcareas groups:

ANATOMICAL AND ORO-FACIAL KEYNOTES (including TMJ)

Keynote	Calcarea carbonica	Calcarea phosphorica	Calcarea fluorica
Skeleton	Resistant	Fragile	Irregular, exostoses
Hand	Strong & thick	Long & narrow	Small, soft & pliable
Perspiration	Localized to head & neck	All over	Very little (skin dry)
Athletic type	Good endurance (fullback)	Lacks endurance but has brilliant bursts of energy (quarterback)	Not well coordinated (team mascot)
Oro-facial	Large, broad head, open fontanelles	Elongated head, open fontanelles	Asymmetrical head
Jaws & Arches	Large elliptical	Narrow elongated elliptical	V-shaped, irregular
Vault (Palate)	Low	Gothic	Narrow & very deep
Tooth Eruption	Delayed & difficult dentition	Early but painful teething	Teeth erupt out of normal sequence
Teeth	White with broad stocky crowns. Upper incisors flat & square. Sensitive to cold	Yellow & long. Upper incisors rectangular with curved facial surfaces	Grey-white teeth. Gum boils, sensitive to pressure & eating, looseness of teeth
Occlusion (bite)	Teeth well aligned	Often malposition in anterior teeth	Irregularly set into arches with sagittal (forward or backward) malposition
TM Joint	Strong & tight	Fine & slack	Hyper-stretch

CONCLUSION

This paper presents a brief overview of the role of homeopathy in dentistry as it relates to acute and chronic prescribing and to the three basic constitutional types. Correct homeopathic prescribing for dental maladies will frequently provoke salutary systemic effects, and this should neither threaten nor alarm us. This is simply a reflection of the natural law of cure and illustrates the fact that the dental apparatus is an indivisible component of the integrated whole person. It cannot be otherwise! And for this we should all be grateful—doctor and patient alike.

Bibliography

Oral Roentgenographic Diagnosis, 3rd ed., Saffne, D.D.S., W.B. Saunders Company, Philadelphia, 1969. p. 82.
Oral Diagnosis, 3rd ed., Kerr, Ash & Millard, C.V. Mosby Company, St. Louis, 1970.
“Etiology of Chronic Periodontal Disease: An Alternative Perspective,” Clark & Carey, Journal of the American Dental Association, Vol 110, May, 1985, pp. 583–589.
Interrelation of Odontons and Tissues in Organs, Field Disturbances and Tissue System, Rheinhold Voll, M.D., M.L. Publishers, Dijal Velzen, West Germany, 1976.
Neural Focal Dentistry—Illness Caused by Interference Fields in the Trigeminal, Ernesto Adler, M.D., D.D.S., Multidiscipline Research Foundation, Houston, 1984.
Electric Acupuncture for Dentistry, John Chan, D.D.S., Nutri-Kinetic Dynamics, Inc., Pearl City, Hawaii, 1980.
Repertory of the Homeopathic Materia Medica, J.T. Kent, A.M., M.D., Indian Books & Periodicals Syndicate, Box 2524, Karol Bagh, New Delhi, 110005.
Materia Medica with Repertory, 6th ed., William Boericke, M.D., B. Jain Publishers, New Delhi, 110055.
“Homeopathy, Holistic Medicine: Terrain, Constitution, Temperament.” M. Tetau, M.D., Journal of Ultra Molecular Medicine, Vol. 1, No. 3, Las Vegas, NV, 1983.
“Understanding Homeopathic Constitutions, Part I.” F. Fuller Royal, M.D., Journal of Ultra Molecular Medicine, Vol. 1, No. 2, Las Vegas, NV, 1983.
“Understanding Homeopathic Constitutions,” Part II. F. Fuller Royal, M.D., Journal of Ultra Molecular Medicine, Vol. 1, No. 3, Las Vegas, NV, 1983.
“A New Concept in Essential Homeopathic Mineral Compositions.” Emile Illovici, M.D., Journal of Ultra Molecular Medicine, Vol. 1, No. 3, Las Vegas, NV, 1983.
“Homeopathy with a Dental Accent.” Richard D. Fischer, D.D.S., F.A.C.D., Homeopathy Today, National Center for Homeopathy, Washington, D.C., March, 1984.
Personal Communication, Kathrine Coulter.

The Effects of cAMP Single Potencies and Mixed Potencies on Acid Phosphatase Activity

Günther Harisch, D.V.M.; Joachim Dittmann, Ph.D.

Reprinted from Biologische Medizin (1999 Feb) 1:4–8.

Abstract

This study investigates whether the effects of cAMP Injeel® and cAMP Injeel® forte in a cell-free system are unique to these preparations or simply equal the additive effects of their single-potency components. When one of the single-potency components of cAMP Injeel® and Injeel® forte was selected as a base potency and the others were added in succession, recorded enzyme activity correlated with the number of potencies added. In all cases, the inhibiting effect of mixed potencies was greater than that of the single potencies, but in no case did the level of inhibition produced by a mixture equal the sum of the effects of its single-potency ingredients.

Introduction

Potency chords are mixed-potency preparations containing equal portions of three potencies of the same substance—a base potency and two additional levels. These potency chords are available commercially under the trade name Injeel®. The “forte” variation includes four rather than three different potencies.¹

The authors confirm the results of the animal experiments reviewed in the article on potency chords in Volume 6/98 of Biologische Medizin (Franke W: Efficacy of Homeopathic Dilutions in the Form of Potency Chords. J Biol Med. 1998;27(6):276–278). The work of the authors on the effects of single and mixed potencies of cAMP on acid phosphatase activity offers additional impressive proof (probability of error 1%; p < 0.01) that potency chords are superior to single potencies in efficacy.

Hartmut Heine, Ph.D.

Materials and Methods

Active Agents

The active substance cAMP was used in the following forms: 6X, 12X, 30X, 200X, cAMP Injeel® (12X/30X/200X), and cAMP Injeel® forte (6X/12X/30X/200X). All preparations were used in liquid form and were supplied in 5 ml ampules by Biologische Heilmittel Heel GmbH, Baden-Baden. (Please note that these cAMP Injeels® are not available commercially.) All cAMP potencies, as well as the Injeel® and its Injeel® forte variation, were produced according to homeopathic principles. The study utilized a blind test format; all preparations were coded prior to use but decoded prior to statistical analysis.

Chemicals

The synthetic enzyme substrate p-nitrophenyl phosphate was supplied by Serva of Heidelberg (Cat. # 30770). All other chemicals used were of the highest available degree of purity.

Enzyme Test System

The enzyme used was acid phosphatase (AP) derived from potatoes (Boehringer, Mannheim; Cat. # 108197). This enzyme model is biologically relevant because acid phosphatase occurs naturally in the lysosomes of human cells. For use in the experimental setups, the enzyme was diluted 1 : 200 with 10 mM of NaAc (pH 5.6).

Incubation Technique

The catalytic activity of AP was measured by determining the amount of p-nitrophenol formed in a microtiter plate assay. 20 µl of the enzyme suspension (out of a total volume of 120 µl) and the cAMP preparation being tested (or water, in the case of the control) were preincubated together at 30 °C. Two series of assays were performed. In one, the preincubation period was 20 minutes; in the other, 40 minutes. After preincubation, each batch of assay components was mixed with 100 µl of the synthetic substrate (5.5 mM p-nitrophenyl phosphate in 0.1 M citrate buffer, pH 5.6) and reincubated at 30 °C. After five minutes, the reaction was stopped by adding 100 µl of 1 N NaOH, and the quantity of enzymatically formed p-nitrophenol was determined using a temperature-controlled microtiter plate reader (ATT C 340, SLT Instruments, Crailsheim) at a wavelength of 405 nm.

The quantity of p-nitrophenol was determined by applying the reference equation p-nitrophenol [nmol × ml⁻¹] = 64.82 × OD 405 nm – 3.373; correlation coefficient 0.998. p-nitrophenol in various concentrations served as the reference substance.

Figure Captions

Fig. 1: Activity of acid phosphatase (AP) in the presence of different cAMP preparations. The graph presents average values (± standard deviation). The line segment ending in circles represents the control. Statistics (n = 48): All experimental mixtures differed significantly from the control (p < 0.01), and 12X differed significantly from all mixtures (p < 0.01). To show the linear relationship among the values more clearly, the y axis begins at 4 instead of at 0, and a line has been drawn connecting the average values for 12X and the Injeel®. The table below the graph shows the composition of the experimental mixtures.

A) Graph (reproduced qualitatively)

(The original plotted mean AP activity [nmol · min⁻¹ · ml⁻¹] ± SD for each setup, y-axis running from 4–10, control marked by ●, and a trend line connecting 12X → Injeel®.)

B) Assay‐Component Table

Component →	12X	12X / 30X	12X / 30X / 200X	Injeel® (12X/30X/200X)
12X	25 µl	25 µl	25 µl	75 µl
30X	–	25 µl	25 µl	–
200X	–	–	25 µl	–
Injeel® stock*	–	–	–	25 µl
Water	75 µl	50 µl	25 µl	25 µl
Enzyme (AP)	20 µl	20 µl	20 µl	20 µl

*In the “Injeel®” column this refers to the mixed‐potency stock (12X / 30X / 200X).

Fig. 2: Activity of acid phosphatase (AP) in the presence of different cAMP preparations. The graph presents average values (± standard deviation). The line segment ending in circles represents the control. Statistics (n = 48): All experimental mixtures differed significantly from the control (p < 0.01), and 30X differed significantly from all mixtures (p < 0.01). To show the linear relationship among the values more clearly, the y axis begins at 4 instead of at 0, and a line has been drawn connecting the average values for 30X and the Injeel®.

A) Graph

(Original mean ± SD plot, y-axis 4–10 nmol·min⁻¹·ml⁻¹, control ●, trend line connecting 30X → Injeel®.)

B) Assay-Component Table

Component →	30X	30X / 200X	30X / 200X / 12X	Injeel® (12X/30X/200X)
30X	25 µl	25 µl	25 µl	–
200X	–	25 µl	25 µl	–
12X	–	–	25 µl	–
Injeel® stock*	–	–	–	75 µl
Water	75 µl	50 µl	25 µl	25 µl
Enzyme (AP)	20 µl	20 µl	20 µl	20 µl

Fig. 3: Activity of acid phosphatase (AP) in the presence of different cAMP preparations. The graph presents average values (± standard deviation). The line segment ending in circles represents the control. Statistics (n = 48): All experimental mixtures differed significantly from the control (p < 0.01), and 200X differed significantly from all mixtures (p < 0.01). To show the linear relationship among the values more clearly, the y axis begins at 4 instead of at 0, and a line has been drawn connecting the average values for 200X and the Injeel®. The table below the graph shows the composition of the experimental mixtures.

A) Graph

(Original mean ± SD plot, y-axis 4–10 nmol·min⁻¹·ml⁻¹, control ●, trend line connecting 200X → Injeel®.)

B) Assay-Component Table

Component →	200X	200X / 12X	200X / 12X / 30X	Injeel® (12X/30X/200X)
200X	25 µl	25 µl	25 µl	–
12X	–	25 µl	25 µl	–
30X	–	–	25 µl	–
Injeel® stock*	–	–	–	75 µl
Water	75 µl	50 µl	25 µl	25 µl
Enzyme (AP)	20 µl	20 µl	20 µl	20 µl

*In the “Injeel®” column this refers to the mixed-potency stock (12X / 30X / 200X).

Setup	Composition	Volumes Added
1	6X	25 µl cAMP 6X + 75 µl water
2	6X / 12X	25 µl 6X + 25 µl 12X + 50 µl water
3	6X / 12X / 30X	25 µl 6X + 25 µl 12X + 25 µl 30X + 25 µl water
4	6X / 12X / 30X / 200X	25 µl 6X + 25 µl 12X + 25 µl 200X + 25 µl water
5	Injeel® forte	100 µl Injeel® forte stock (6X/12X/30X/200X)
6	Control	100 µl water

Fig. 4: Activity of acid phosphatase (AP) in the presence of different cAMP preparations. The graph presents average values (± standard deviation). The line segment ending in circles represents the control. Statistics (n = 48): All experimental mixtures differed significantly from the control (p < 0.01), and 6X and 6X/12X differed significantly from Injeel® forte (p < 0.01). To show the linear relationship among the values more clearly, the y axis begins at 4 instead of at 0, and a line has been drawn connecting the average values for 6X and the Injeel® forte. The table below the graph shows the composition of the experimental mixtures.

A) Graph

(Original mean ± SD plot, y-axis 4–10 nmol·min⁻¹·ml⁻¹, control ●, trend line connecting the series 6X → Injeel® forte.)

B) Assay-Component Table

Component →	6X	6X / 12X	6X / 12X / 30X	6X / 12X / 30X / 200X	Injeel® forte (6X/12X/30X/200X)
6X	25 µl	25 µl	25 µl	25 µl	–
12X	–	25 µl	25 µl	25 µl	–
30X	–	–	25 µl	25 µl	–
200X	–	–	–	25 µl	–
Injeel® forte stock*	–	–	–	–	100 µl
Water	75 µl	50 µl	25 µl	25 µl	–
Enzyme (AP)	20 µl	20 µl	20 µl	20 µl	20 µl

*In the “Injeel® forte” column, this refers to the mixed-potency stock (6X / 12X / 30X / 200X).

Statistics

The measured values obtained for all setups (activity per volume in nmol × min⁻¹ × ml⁻¹) were subjected to single-factor variance analysis (ANOVA). Subsequently, the Fisher LSD test was performed to directly compare the effect of the control to that of each cAMP preparation or stage in the additive series of cAMP potencies. A probability of error of 1% (p = 0.01) was chosen as the limit of significance.

Results and Discussion

cAMP Injeel®

The cAMP Injeel® used in these experiments is a 1 : 1 : 1 mixture of the single potencies 12X, 30X, and 200X. In numerical terms, adding 75 µl of this mixture to a setup adds 25 µl each of 12X, 30X, and 200X. The design of our experiments took this fact into account, as exemplified by Series 1 (Figure 1):

Setup 1 (12X) contained 25 µl of cAMP 12X and 75 µl of water.
Setup 2 (12X/30X) contained 25 µl each of 12X and 30X, plus 50 µl of water.
Setup 3 (12X/30X/200X) contained 25 µl each of 12X, 30X, and 200X.
Setup 4 (Injeel®) contained 75 µl of cAMP Injeel® and 25 µl of water.
Control contained 100 µl of water.

Each setup was mixed with 20 µl of AP suspension and preincubated at 30 °C. After 20 minutes, 100 µl of the substrate solution were added and incubation was continued for five more minutes. The reaction was then stopped and the quantity of enzymatically formed p-nitrophenol was determined through spectrophotometry.

As Figure 1 shows, all cAMP preparations inhibited the catalytic activity of AP. A linear decrease in enzyme activity is apparent in the series 12X → 12X/30X → 12X/30X/200X → Injeel®. A similar tendency was observed both when 30X was chosen as the base potency and 200X and 12X were added one at a time (Figure 2), and when 200X was chosen as the base potency and 12X and 30X were added (Figure 3).

A linear decrease in AP activity was also apparent when the preincubation period was increased from 20 to 40 minutes. Inhibition of AP was more moderate, however, and the recorded values were different (data not shown).

cAMP Injeel® forte

cAMP Injeel® forte is a mixed potency consisting of equal parts of the single potencies 6X, 12X, 30X, and 200X; thus, 100 µl of this mixture contains 25 µl each of 6X, 12X, 30X, and 200X. See the table for the components and test sequence leading to the Injeel® forte variant.

The experiments were conducted in the same way as the Injeel® experiments. As Figure 4 shows, all of these cAMP preparations inhibited AP catalytic activity. A linear decrease is again apparent in the series leading from 6X to the Injeel® forte. The same phenomenon is apparent when 12X, 30X, or 200X is chosen as the base potency (data not shown).

From these results, we can conclude that the effects of cAMP potency chords are not identical to the sum of the effects of the individual potencies they contain. As this example shows, potency chords such as Injeel® or Injeel® forte preparations seem to have qualitatively new and unique effects. Further investigation will be needed in order to determine whether this conclusion also applies to Injeel® and Injeel® forte preparations of other substances.

References

Wissenschaftliche Abteilung der Firma Biologische Heilmittel Heel GmbH. Ordinatio Antihomotoxica et Materia Medica. Baden-Baden. 1996:13.
Stryer L. Biochemie. 4. Auflage. Heidelberg: Spektrum. 1996:779–802.
Harisch G, Dittmann J. Untersuchungen zur Wirkung von Ubichinon-Injeel und Injeel forte mit zellfreien Systemen. Biol Med. 1997;26(3):99–104.
Harisch G, Dittmann J. Einfluss von cAMP-Potenzen auf die katalytische Aktivität der Sauren Phosphatase. Erste Hinweise für divergierende Wirkungsqualitäten von Einzelpotenzen und Potenzmischungen. Biol Med. 1998;27(5):212–219.

For the authors

Joachim Dittmann, Ph.D.
Institute for Physiological Chemistry
Veterinary College of Hannover
P.O. Box 71 11 80
D-30545 Hannover
Germany

August 2, 2025

Alternatives to the use of Cortisone
J. Kersschot, M.D.
Belgium

BioMedical Therapy Magazine Symposium
At the Royal Society of Medicine, London
10. 5. 1997

A. Introduction

Although the use of corticosteroids is accepted as a standard technique in the treatment of several inflammatory diseases, we must recognize that specific injection techniques of anti-inflammatory products are gaining more and more interest. Most physicians, however, tend to regard these techniques as marginal phenomenons. The importance of these injections in the treatment of so-called inflammatory diseases is relatively unexplored and promises to be a fertile area for further investigation.
Since most physicians have never been trained in these techniques, they are anything but expert in this field. I think that every therapist should at least know about the existence of this strategy, even if he or she will not use injections in his or her own practice.
So, I will introduce to you today the therapeutical strategies that focus on injections of non-steroid products. Both chemotherapeutic and biotherapeutic products will be discussed, and several techniques of administrating them will be explained. The clinical cases will try to illustrate my strategies.
I have more than ten years of experience with these techniques in my private practice as a general practitioner in Belgium, and I have noticed that there is a very broad spectrum of medical problems that can be managed with this injection strategy. Today, however, I will only discuss two examples of alternatives for cortisone: the treatment of musculoskeletal pain and the treatment of asthma.
Still, I do not make any claims about the injections described in this lecture, involving the prevention or cure of any disease. Maybe the effects that I have noticed in my private practice are no more than a sophisticated placebo. I cannot be sure that what I am doing is best for the patient unless this practice has been rigorously tested; to check the items that I suggest, large-scale clinical studies are necessary. This lecture can be regarded as an invitation to do so in the near future.

B. Injection of biotherapeutics

B.1. Injection of biotherapeutics is not a very strategic novelty

Those familiar with biotherapeutics for injection know that many ampoules exist since several decades, especially in Germany. Especially Heel, Pflüger, Steigerwald, Dolisos, Cosmochema, Fides and Hevert are famous for their ampoule preparations. Thousands of them are injected every day, and clinical studies check their efficiency and control their possible side-effects (ref. 20, 21, 28, 29). A wide selection of homeopathic and phytotherapeutic preparations has been on the market in injection form for many years now, and they have been employed in daily medical practice with good success, especially by general practitioners, rheumatologists and orthopaedic doctors. Many authors have already mentioned the use of biotherapeutic ampoules for injection: Bianchi (ref. 3), Claussen (ref. 13), Coeugniet, de La Fuye (ref. 31), Diamond (ref. 44, 45), Fischer (ref. 36), Frase, Gellman (ref. 19), Graf von Ingelheim (ref. 27), Geyer (ref. 24), John, Kleinscholt, Küstermann, Lannugier-Bolling, Meltelmann (ref. 28, 29), Müller, Pollmann, Potrafki (ref. 21), Preusser, Reckeweg (ref. 14), Riley (ref. 16), Risch, Schmid (ref. 17), Subotnick (ref. 43, 48), Thiel (ref. 20), Timmermann (ref. 10), Vorstoffel (ref. 33), Wachter, Werthmann, Weiser (ref. 28), Zenner (ref. 29) and many others (see ref. 1: bibliography).
Since there was no specific name for all the methods that use biotherapeutics for injection on specific spots, I introduced in Belgium the term ‘biopuncture’ (ref. 1, 2, 5), in order to distinguish the use of homeotherapy according to de La Fuye (ref. 31), neural therapy according to Huneke (ref. 11), ampoules over nerve blocks according to Bracho (ref. 12) and segmental acupuncture according to Pistor (ref. 32). At the same time we want to give more credibility and respect to orthodox doctors as to therapists in natural medicine (ref. 1, ref. 8). In this way, we shall stimulate its use, so that the strategy of using these injections is developed in everyday practice.
Let us now go a little deeper:

C. Biotherapeutics for local injections?

C.1. Subcutaneous injection

One of the most familiar ways of using biotherapeutics in everyday practice. Most of you use them in the oral form, as tablets or drops.
Although you may not be interested in giving injections in your practice, I think it is good to know more about the enormous possibilities of these biotherapeutic drugs. And it might give you a broader view on natural medicine, because injections can act in a more powerful way than oral medication.
The exact choice of the remedy itself (ref. 1, 2, 5).

C.2. Acupuncture point injections

Those doctors familiar with acupuncture, can enhance their therapeutic effect by injecting intracutaneously or subcutaneously a biotherapeutic product instead of dry needling. This method was mentioned before by de La Fuye, Geyer, Matz, Frase and many other authors.
It is theoretically possible to inject a single remedy into an acupuncture point that is known for certain indications. This combination of homeopathy and Chinese medicine (homoeosinaty) was introduced by de La Fuye. I will give you some examples:

Chelidonium on Liver 13 for drainage of the liver,
Nux Vomica on Bladder 21 for gastritis,
Gnaphalium on Bladder 34 for ischias,
Sulfur on Bladder 52 for eczema,
Cantharis on Kidney 11 for cystitis,
Lobelia on Kidney 27 for asthmatic bronchitis,
Naja Tripudians on Bladder 17 for cardiac neurosis,
Crataegus on Heart 3 for palpitations,
Thuja on Gallbladder 30 for coxarthrosis,
Echinacea on Jenn Mo 19 for cough, asthma, bronchitis
Echinacea on Jenn Mo 22 (for cough, asthma, bronchitis),
Lachesis on Small Intestine 19 for vertigo,
Sulfur on Bladder 31 for climacteric disorders.

Cralonin on Heart 3 for palpitations,
Cralonin on Bladder 15 for palpitations,
Engystol on Small Intestine 14 for asthma,
Vertigoheel on Small Intestine 19 for vertigo,
Mullein pro injectione on Urinary Bladder 31 for climacteric disorders,
Traumeel on Gall bladder 20 for headache,
Spigelon on Gall bladder 20 for headache,
Zeel on Gall bladder 30 for pain in the hip region,
Pulsatilla composition on Jenn Mo 6 for activation of the defensive system.

It is also possible to inject a complex remedy into several points of an acupuncture meridian, like for example Discus compositum over the Governor vessel. Subcutaneous or intracutaneous injections are given on the mid-line of the back, or at the level of every vertebra in the region of the pain.
Those allopathic products should always be used in a diluted way (half a normal dose, adding several ml of physiological fluid and several ml of a local anesthetic), and should be injected with more care than the biotherapeutic one. I use them as a replacement for corticosteroid injections (see also ref. 51). Of course, some injections are given at the physician’s own responsibility, when the product is used in a way for which it has not been registered. Ticlodil is officially designed for the intravenous/intramuscular injection only and an oral Feldene is officially designed for the intramuscular injection only. So, I can not make any claims about their safety and efficacy, until more large-scale clinical studies are performed.

F. Is it always necessary to give injections?

For those therapists who are not allowed to give injections, I can recommend to do trigger point therapy with stretch and spray, as Travell and Simons suggest. This is an easy and safe technique, and gives interesting results when dealing with several myofascial disorders. The patient is usually very enthusiastic, since he or she has almost immediate relief. Although this effect is temporary, long term effects are achieved with repeated sessions.
Even more interesting is ischemic compression. Ischemic compression is application of progressively stronger, painful pressure on a trigger point for the purpose of eliminating the trigger point’s tenderness and hyperirritability. Similar to acupressure and shiatsu, the thumb is used as the therapeutic tool. But we do not deal with acupuncture points, but solely with active trigger points, which can be found by clinical examination. The thumb action blanches the compressed tissues, which usually become flushed (hyperemic) on release of the pressure. The use of Traumeel ointment during and after the compression, enhances the effects of the treatment.
The clinical effects of the technique depend largely on the skills of the therapist. When looking for the active trigger points, wall plates can help. Textbooks (by Baldry, Travell and Simons) give more fundamental information on this subject. In Belgium, I am giving workshops on trigger point therapy, in order to show how this technique can be performed in everyday practice.

Case:

Clinical examination shows a painful zone in the right brachioradialis muscle and a small spot at the epicondylus radialis, that is painful on digital pressure. He had ischemic compression on two trigger points in the brachioradialis muscle, twice a week.
He also got a local application of Arnica comp. ointment (e.g. Traumeel) in the right brachioradialis muscle and on that small painful spot at the epicondylus radialis, three times a day. Additional oral treatment with Ferrum-Homaccord, ten drops three times daily, gave complete relief after two weeks.

Case:

A girl of twelve has suffered a contusion of the lateral part of the thigh while snowboarding. The examination on the evening shows an obvious swelling of the thigh and an extensive haematoma. The region is very sensitive to pressure, and she refuses a local injection. I give her Arnica comp. ointment (Traumeel ointment, which was cooled in the fridge) and she applied it every hour the first day, every two hours the second and third day and four times a day the three next days. Putting the ointment in a refrigerator before application gives an extra cooling down in an acute situation. As an additional therapy, she received Arnica comp. tablets: I told her to take them at the same frequency as the application of the ointment. I asked her to keep the tablets in the mouth as long as possible, to give the product maximum resorption via the oral mucosa. After six days the pain and swelling were completely gone.

G. Conclusion

Although the use of corticoids is accepted as a standard technique in the treatment of several inflammatory diseases, we must recognize that specific injection techniques of biotherapeutic products are gaining more and more interest. Most physicians, however, are not familiar with these techniques. That is why I wanted to show the importance of these injections in the treatment of so-called inflammatory diseases.
By using biotherapics (drops or tablets), I have experienced that the combination of oral application (drops or tablets) and local treatment (ointment and/or injections) gives interesting results, both in acute as in chronic cases.
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11. Geyer, E.,
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12. Rubin, D.,
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13. Werthmann, K.,
  Antihomotoxische Therapie der viszeralen Erkrankungen
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14. Zenner, S.,
  Behandlung der Gonarthrose mit Zeel P Injektionslösung – Ergebnisse einer Anwendungsbeobachtung
  Biologische Medizin, Heft 4, August 1993, 193-201
15. Wesler, M., Metelmann, H.,
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16. Zenner, S., Metelmann, H.,
  Application Possibilities of Traumeel S Injection Solution
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18. de La Fuye, R.,
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19. Pistor
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20. Vorstoffel, E.,
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21. Tirscher H, Eder M,
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22. Bruns, J.,
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23. Fischer J,
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24. Saal J S, Saal A J, Yurth E.,
  Nonoperative Management of Herniated Cervical Intervertebral Disc With Radiculopathy
  Spine 1996; 16: 1877-1883
25. Conroy J M, Ginsberg F, Léon M, Bernard V, Appelboom T, Haazen L,
  Peri-articular injection of Tenoxicam for painful shoulders: a double-blind, placebo-controlled trial
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26. Melzack R, Cibson C.Z, Simons L S,
  Trigger point therapy and referred pain
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27. Fairbank J C T, Park W M, McCall I W, O’Brien J P,
  Apophyseal injection of local anesthetic as a diagnostic aid in primary low-back pain syndromes
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28. Hong C-Z, Hsueh T C, Yu S,
  Recurrent myofascial trigger points related to traumatic cervical disc herniation
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29. Gunn C C, Milbrandt W E,
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  Am J Acupuncture 1977; 5: 61-66
30. Subotnick I,
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31. Diamond W J,
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32. Diamond W J,
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33. Werthmann K,
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34. Lanninger-Bolling D,
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35. Subotnick I,
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36. Schmid F.,
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37. Rich B, Mc Keag D,
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38. Kersschot, J.,
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39. Kersschot, J.,
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  Antwerp, Congress movement counselors; 22.3.1997
40. Potrafki B,
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41. Kersschot J,
  The use of trigger point injections for low back pain
  Workshop injuistingen, Gent (Belgium): 18. 2. 97
42. Kersschot J.,
  Alternatives to the use of cortisone
  Antwerp, Congress movement counselors; 22.3.1997
43. Matusiewicz, R.,
  Traumeel S in der Behandlung von kortikoidabhängigen Bronchialasthma
  Biologische Medizin 1996; 3: 107-112
44. Zenner, S., Metelmann, H.,
  Application Possibilities of Traumeel S Injection Solution: Results of a Multicentric Drug Monitoring Trial Conducted on 3,241 Patients
  Biological Therapy 1992; 4
45. Zell, J., Conrert, W. D., Mau, J., Feuerstake, G.,
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48. Matusiewicz, R.,
  Wirksamkeit von Engystol N bei Bronchialasthma unter kortikoidabhängiger Therapie
  Biologische Medizin 1995 ;5: 242-246
49. Frase, W., Wesler, M.,
  Intrartikuläre Behandlung der Gonarthrose mit Zeel comp. – Ergebnisse einer Anwendungsbeobachtung
  Biologische Medizin 1996; 3: 115-119
50. Ricken, K.–H.,
  Antihomotoxische Therapie als alternative vor cortison
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51. Thiel W, Borho B,
  Die Therapie von frischen Hämatrosen mit Traumeel Injektionslösung
  Biologische Medizin 1991 nr.2, 506-515
July 23, 2025
AUTO-SANGUIS THERAPY
According to the teachings of Reckeweg’s homotoxicology, virtually every illness may be defined as either a defensive reaction by the organism against toxins or as the expression of toxic damage. It follows, therefore, that the blood of each patient contains those pathogenic poisons (homotoxins) typical of the disease from which that patient suffers.

Through withdrawing a patient’s blood, then homeopathically potentising it over several levels and subsequently re-introducing it by means of hypodermic injection, Reckeweg holds that precisely these pathogenic poisons undergo modification to yield a homeopathically active therapeutic agent ideal for application in stimulation therapy. This agent stimulates the body’s defense systems thus increasing detoxification and promoting the healing process.

According to Burgi’s Principle, the injection of appropriate homeopathic preparations intensifies efficacy of the potentised auto-sanguis blood to an even higher degree.

Auto-sanguis therapy is a treatment designed to exert a counteractive effect against exogenic and endogenic homotoxins (including toxic deterioration of by-products from the body’s own cells), thus promoting the healing of chronic disease in harmony with the laws of nature.

AUTO-SANGUIS: PROCEDURE
1. Withdraw 2–3 cc of the patient’s blood
2. Expell contents of syringe
3. Using the syringe and needle initially used for blood withdrawal, aspirate the appropriate Heel remedy (injeel, suis organ, etc.). It is best to use no more than 3 remedies. Once the remedy is in the syringe, cap the syringe and shake vigorously, about 10 times to potentise the mixture.
This is the first potentisation which is then injected into the patient s.c. or i.m. (and i.a. & i.p. in an experimental nature).

Intravenous injection is contraindicated in auto-sanguis therapy, as the degree of potentisation would be lost, and the intended action on the immune system would become questionable.

Potentisation can be carried out up to 5 times. The number of stages you select should be adjusted according to your prognosis, professional judgment and familiarity with the patient.

CONDITIONS THAT MAY BENEFIT FROM AUTO-SANGUIS THERAPY:
- Iatrogenic conditions
- Chronic viral and bacterial infections
- Precancerous stages
- Hepatic damage
- Migraine
- Chronic eczema
- Bronchial asthma
- Duodenal and gastric ulcers
- Arthrosis
- Lymphatic diathesis
PROTOCOL FROM A CASE STUDY
Case study by: Drs Ivo Bianchi & Jo Serrentino

RE: 40 year old female Caucasian

CONDITION: Lower back pain due to strain and possible cervical hernia. X-rays showed a small deviation (less than 5 degrees) of vertebra #5, without arthrosis or calcification. This deviation was congenital and no damage seemed evident. The condition worsened because of irritation of the sciatic nerve due to overexertion.

PROCEDURE: 1–2 cc of patient’s blood was drawn into a sterile syringe. The blood was discarded, leaving only minute traces of the patient’s blood in the syringe. 2 cc of Discus compositum, 2 cc of Traumeel and 2 cc of Zeel were then aspirated into the emptied syringe (that still had traces of the patient’s blood). The injection was given s.c. in the region of the 5th vertebra.

RESULTS: Although this patient’s condition was not serious or degenerative, but rather from injury, it was very painful and restricted movement. A treatment to relieve and, mostly halt the progress of the condition, was imperative. The auto-sanguis treatment was followed with intravenous injection of Traumeel and with the oral administration of Zeel, Traumeel and Discus comp. fragmented over two weeks.

The patient claimed relief almost immediately, with a slight exacerbation within hours of the treatment lasting about 4 hours. The following day the patient was able to resume normal movement which progressively improved to full recovery without recurrence within the three year follow up period.
July 23, 2025
Introduction to Neural Therapy
by HEEL Medical – Scientific Department

What does neural therapy involve?

Neural therapy involves curative procedures which act via the autonomic nervous system. Techniques of neural therapy were developed from procedures applied for local anesthesis by the two brothers and general practitioners Dr. Ferdinand Huneke and Dr. Walter Huneke, both medical doctors in Düsseldorf.

Neural (Greek)

Of, relating to, or affecting a nerve or the nervous system.

Neuron

Nerve cell, nerve tracts, neuron theory

Neuron theory

The original version of the neuron theory, as published by Ramon y Cajal in 1934, stated that each nerve cell (i.e., neuron) represents an anatomical, genetic, functional, and regenerative unit.

The latest insights gained from electron-microscopic findings have confirmed the reality of synapses as physically and anatomically verified sites of junction: between two neurons (i.e., an interneuronal synapse) and between a neuron (peripheroreceptor) and the locus of action (i.e., a neuro-receptor synapse). These insights, in conjunction with complementary findings, represent the confirmed scientific basis for the entire fields of neurohistology, neurophysiology, and neuropathology.

The significance of neural therapy: Neural therapy involves curative techniques administered via the autonomic nervous system. The autonomic nervous system is a functional unit which includes the neurohumoral regulatory system in its overall mode of reflectoral operation. The autonomic nervous system encompasses the sympathetic nervous system, the parasympathetic nervous system, and the basic autonomic neural system. This basic autonomic neural system is the interstitial, soft connecting tissue which fills all organ interstices. It is composed of cells, nerves, capillaries, and extracellular fluid. This system plays the role of a communicator in the overall arrangement which enables each cell in the body to be in connection with every other cell. The autonomic nervous system is that part of the entire central nervous system which is of significance for the maintenance and reproduction of the particular organism involved. The autonomic nervous system primarily serves for control of the inner milieu. Since the control loops of the autonomic and somatic nervous systems are multiply interlinked at all synapse stages of the central nervous system, the functioning of the autonomic nervous system is not in fact strictly autonomous in nature.

The autonomic nervous system differs from the somatic nervous system in the following significant aspect:
- Connections to the periphery are not uniformly present.
- These connections are also subject to interruption by intermediate ganglionic stations (in which the ganglia are groups of nerve cell bodies). In the autonomic nervous system, sympathetic and parasympathetic ganglia are involved.
Human life is possible only in conjunction with the hermetic control of all regulation mechanisms. The pathways of the autonomic nervous system have the function of passing stimuli. Excessive stimuli disturb or block the development of energy and, in turn, the distribution of this energy. All neural therapeutic methods feature the introduction of energy to the impaired tissue, or they effect removal of the blockage by energy transfer. These procedures, however, also initiate reactions which are capable of eliminating damage which has already occurred. The body’s defense system, with its mechanisms of self-healing, is thereby stimulated to action.

All neural therapeutic techniques in the broad sense utilize this approach: acupuncture, chirotherapy, cutaneous and other types of stimulation, and cupping. And the same applies for neural therapy in the narrow sense: concerted injection therapy with local anesthetic.

HISTORICAL SUMMARY OF NEURAL THERAPY

Neural therapy by means of local anesthetic was discovered orientationally by Ferdinand and Walter Huneke. The Huneke brothers, both medical doctors from a family of physicians, had attempted unsuccessfully for years to treat their sister’s migraine attacks.

Atrophanyl, a new medication for rheumatism, was introduced onto the market in 1925. On the advice of a colleague, Ferdinand Huneke treated his sister by intravenous injection of the new preparation. The therapy immediately interrupted the migraine attack, with all its accompanying symptoms. Only one single subsequent administration, with the same success, was required to completely free his sister of her long-term suffering.

The two brothers were naturally impressed by the success of their treatment, but they could not explain the effects. They eventually determined, however, that Atrophanyl was available in the following two types:
- For intravenous administration, without 2% addition of cocaine
- For intramuscular administration, with 2% addition of cocaine
In his treatment of his sister, Ferdinand had confused the two solutions and had mistakenly administered the procaine solution intravenously – a form of administration which had until that time been expressly forbidden. It was believed then that procaine could damage important centers in the brain.

Motivated by the unexplained success of the therapy, the brothers then began to separately study the causative factors behind the accidental cure.

The two brothers independently discovered that the positive effect of the procaine was not only associated with the mode of administration (i.e., intravenous injection), but that the determining criterion for the therapeutic results was most probably the specific point of the injection. They wondered whether previously unknown reflex-type reactions could possibly act via Head’s zones.

Beginning with these findings, Ferdinand and Walter Huneke used injections administered at particular points to treat conditions of pain in the respectively segment-associated areas of the body. They named their technique “therapeutic anesthesia,” until Kibler, a friend, proposed a better name: “segment therapy with local anesthesia.”

In 1928, the Huneke brothers published their findings in Medizinische Welt under the title, “Unexpected Remote Therapeutic Effects of Local Anesthesia.”

Neural therapy as developed by the Hunekes is administered in two forms:
- A. Segment therapy: Concerted injections of anesthetic into the segmental area associated with the illness.
- B. Elimination of a focal disorder: Rendering a causal focal disorder ineffective by means of a neural therapeutic agent acts as causal therapy, with the elimination of complaints and pain in seconds (the so-called Huneke phenomenon), including pain without segmental association.
Definition of focal disorder

A focal disorder is chronically altered tissue which causes remote disorders via neural paths. A focal disorder is considered to be any pathological alteration which possesses the ability to cause remote disorders beyond its immediate locale.

Location of focal disorders

Pinpointing of the focus responsible for a disorder begins with preparation of a concerted case history, and includes systematic injections at potential foci.

SEGMENT THERAPY

Segment therapy is based on the insight that all parts of a bodily segment respond by reflection, as a unit, to particular processes. Stimulation pulses proceed from the body’s periphery, via the spinal cord, to the segment-associated organ, and vice versa. Pulses also travel along the dermato-visceral reflex path, or from an organ via the spinal cord to other organs—as well as along the viscero-visceral reflex path.

IMPORTANT: In all cases it is the entire human being which becomes ill, and never only one isolated organ. Concerted neural therapy not only interrupts pathological reflex paths, but also normalizes all autonomic neural functions through repolarization of the stimulus-disordered cell-membrane potentials.
- Most important therefore is the point at which the injection is performed, and only to a lesser degree the particular medication which is administered. Segment therapy is genuine treatment in the original sense of the Latin origin “tractare,” to handle—a laying on of the hand.
Head’s zones

These zones were named for the work of Sir Henry Head, a London neurologist (1861–1940). These are hyperesthetic-hyperalgesic zones which appear on the surface of the human trunk in conjunction with disorders of certain inner organs, and which are characterized by heightened cutaneous sensitivity. This phenomenon has been explained by the fact that these cutaneous zones are provided with their sensitive innervation (nerve supply) from the same neural segments which supply the disordered organ.

Disordered sensitivity is also often found together with alterations of muscle tone (defense musculaire—for example, appendicitis), involving the viscero-cutaneous reflex.

What is meant by “chronically altered tissue”? Non-vital teeth, points of focal infection, tonsils as foci, scars on the surface of the skin or deeper in the body, scars on bones, foreign bodies, chronically inflamed organs (e.g., appendicitis chronica), and residual conditions after inflammatory processes which have subsided; e.g., in the ears and sinus cavities, at the gall bladder, at the appendix, in the female genital tract, and in the prostate.

HUNEKE’S INSTANTANEOUS PHENOMENON

In 1941, Ferdinand Huneke discovered that there are foci located on neural paths and not subject to any segmental assignment, yet capable of initiating and maintaining certain illnesses. These foci can be rendered ineffective in the neural-therapeutic sense by the concerted administration of local anesthetics. The disorders caused by the treated foci will then immediately vanish as a result of Huneke’s so-called flash phenomenon.

Huneke’s flash phenomenon is involved if all three of the following conditions are met:
1. All symptoms vanish instantaneously and completely.
2. Freedom from the symptoms continues for at least twenty hours.
3. The above phenomena are repeated with recurring symptoms.
If all conditions are met, injections are continued at intervals of one week—with the periods between injections gradually lengthened—until a complete cure is achieved.

Important: If, however, significant improvement is not achieved by injections into the segment, and if the flash phenomenon is not observed in the suspected focus, then injections at this point are futile, and the search for the proper focus must continue.

N.B.: The most important factor in neural therapy is the point of injection, and not the particular medication injected.

THE TECHNIQUES OF NEURAL THERAPY

Instruments required
- Single-use cannulae
- Single-use syringes (5‑ml plastic syringes have proved most effective for focal disorders)
- A neural therapeutic agent.
Dosage and manner of application will vary considerably from case to case.

Wheal test

Raised, beetlike efflorescence with a red areola, as the expression of an acute edema of the skin.

Wheal test method: If a wheal applied intracutaneously with 0.2 ml of isotonic saline solution is no longer evident after 40 to 45 minutes, the patient has a propensity to develop edema. Disappearance of the wheals within 3 to 30 minutes indicates pronounced edema tendency.

DEFINITIONS
- Neural therapy: Treatment of a disease via the autonomic nervous system.
- Autonomic nervous system: A functional unity which includes the entire conditional-reflectorally functioning neuro-humoral system of regulation.
- The autonomic nervous system includes:
  - The sympathetic nervous system
  - The parasympathetic nervous system
- Basic autonomic neural system: An interstitial (i.e., located in intermediate tissue), soft connecting tissue which fills the interstices between organs. It is composed of cells, nerves, capillaries, and the extracellular liquid space. This system performs communicative functions required to provide connection between each cell of the body and every other cell.
- Segment therapy: Therapy administered in a segment via Head’s zones. Deeper-lying organs are accessed via dermato-visceral reflex paths (as defined by Pischinger).
- Focal therapy: If no success is achieved after repeated local or segment therapy, it may be assumed that a focal disorder is responsible for the complaint. It is then necessary to search for the responsible focus.
- Local therapy: Direct administration of neural therapeutic agents which enables long-term freedom or relief from symptoms.
- Procaine: p-aminobenzoyl diethylaminoethanol hydrochloride; the most frequently used local anesthetic; weak in its effects, non-toxic, and not harmful to human tissues.
- Local anesthetic: An agent which, when locally administered, reversibly eliminates the excitability and conductivity of nerves or their endings. The area involved then becomes insensitive to pain.
- Local anesthesia: Insensitiveness to pain in a locally restricted area of the body.
July 23, 2025
Lymphomyosot minimizes the risks associated with diabetic neuropathy
Activates the lymphatic system

The efficacy of Lymphomyosot for the treatment and prevention of lymphatic disorders has been demonstrated in numerous studies¹–⁵.

Extremely well tolerated

In a study of 3,512 patients, including 1,124 (32%) children under 10 years of age, 99.8% assessed Lymphomyosot therapy as “very well tolerated” throughout the course of treatment¹.

3 different dosage forms
- Drops: 15 drops 3 times per day
- Tablets: 3 tablets 3 times per day
- Ampoules: 1 ampoule 1 to 3 times per week
As a standard for comparison, 10 infusions with 600 mg of α-lipoic acid over 8 months improved tactile sensitivity among study patients by only Ø +0.9. However, a combination therapy with Lymphomyosot (15 drops twice daily for 8 months) and α-lipoic acid (10 infusions with 600 mg of α-lipoic acid over 8 months) improved tactile sensitivity by Ø +3.25⁵.
- Neural nutrient insufficiency
- Diminished tactile sensitivity
- Defence reaction absent
- Risk, imbalance, damage
- Amputation
- Gangrene
- Diabetes
- Diabetic foot
- Inflammation
- Malfunction/glycosylation of the matrix
- Peri-neural oedema
Reduction of oedema

Severity of symptoms Start Reduction No reduction
Slight 14 10 4
Moderate 26 19 7
Severe 0 9 1

50 patients diagnosed with diabetic neuropathy were administered 15 drops of Lymphomyosot twice daily for 8 months. At the end of the treatment period, lymphoedema and tactile sensitivity had profoundly improved⁵.

Improvement of tactile sensitivity

Severity of symptoms Start End Difference
Slight 5.0 7.5 +2.5
Moderate 3.0 6.0 +3.0
Severe 0.0 3.0 +3.0

Minimizes the risks associated with diabetic neuropathy
- Improved matrix metabolism
- Improved tactile sensitivity
- Eliminated pain in 75% of patients
- Lymphatic disorders
- Recurrent infections
- Detoxification and drainage
Lymphomyosot – recommended for
- Lymphhoedema (i.e. for promoting postmammectomy drainage)
- A compromised defence system (i.e. for treating recurrent and acute infections, and inflammatory disorders such as tonsillitis or lymphangitis)
- Tonsillar hypertrophy
- Lymphadenitis
- Systemic toxicities (i.e. for treating chronic diseases or amalgam-related disorders)
Composition:
- Drops: 100 g cont.: Myosotis arvensis D3, Veronica officinalis D3, Teucrium scorodonia D3, Pinus silvestris D 4, Gentiana lutea D 5, Equisetum hyemale D4, Sarsaparilla D6, Scrophularia nodosa D3, Juglans regia D3, Calcium phosphoricum D12, Natrium sulfuricum D4, Fumaria officinalis D4, Levothyroxinum D12, Araneus diadematus D6 5 g each; Geranium robertianum D4, Nasturtium officinale D4, Ferrum jodatum D12 10 g each. Contains 35 vol.-% alcohol.
- Tablets: 1 tablet cont.: Myosotisarvensis D3, Veronica officinalis D3, Teucrium scorodonia D3, Pinus silvestris D4, Gentiana lutea D5, Equisetum hyemale ex herba rec. D4, Sarsaparilla D6, Scrophularia nodosa D3, Juglans regia D3, Calcium phosphoricum D12, Natrium sulfuricum D4, Fumaria officinalis D4, Levothyroxinum D12, Araneus diadematus D6 5 g each; Geranium robertianum D4, Nasturtium officinale D4, Ferrum jodatum D12 10 g each.
- Injection solution: 1.1 ml cont.: Myosotis arvensis D3, Veronica officinalis D3, Teucrium scorodonia D3, Pinus silvestris D4, Gentiana lutea D5, Equisetum hyemale D4, Sarsaparilla D6, Scrophularia nodosa D3, Juglans regia D3, Calcium phosphoricum D12, Natrium sulfuricum D4, Fumaria officinalis D4, Levothyroxinum D12, Araneus diadematus D6 0.55 µl each; Geranium robertianum D4, Nasturtium officinale D4, Ferrum jodatum D12 1.1 µl each.
Indications: Status lymphaticus (tendency to hyperdevelopment of the lymphatic organs; tendency to development of oedemas and infections); glandular swelling; tonsillar hypertrophy; chronic tonsillitis.
Contraindications: In case of thyroid disorders, this preparation may not be administered without prior approval from a physician.
Side effects: None known.
Interactions with other medication: None known.
Dosage: Drops: In general, 15-20 drops 3 times daily. Tablets: In general, 3 tablets to be dissolved in the mouth 3 times daily. Injection solution: In acute disorders daily, otherwise 3-1 times weekly 1 ampoule i.m., s.c., i.d.
Package sizes: Drops: Drop bottles containing 30 and 100 ml. Tablets: Packs containing 50 and 250 tablets. Injection solution: Packs containing 10, 50 and 100 ampoules of 1.1 ml.
Revised: April 2001.

References
1. Zenner S, Metelmann H: Therapeutic Use of Lymphomyosot® – Results of a Multicentre Use Observation Study on 3,512 Patients. Biological Therapy 1990, Vol Vlll No. 3.: 49–53,67–72, and Vol Vlll, No. 4: 79–84, 94
2. Küstermann K, Weiser M: Treatment of a Lymphatic Disease with Homoeopathic Therapy. Biologische Medizin 1997; Vol 26 No. 3: 110–114
3. Rinneberg A-L: Lymphomyosot®: The Therapy of Tonsillitis and Prophylaxis against its Recurrence. Biological Therapy 1991; Vol IX No. 1: 111–114
4. Riley D, White S: A Biotherapeutic Approach to the Treatment of Inflammatory Disorders: A Drug Monitoring Trial. Biological Therapy 1992; Vol. X No. 3: 267–271
5. Dietz R: Possibilities of Lymph Therapy with Diabetic Polyneuropathy. Biologische Medizin 2000; Vol 29 No. 1: 4–9
July 22, 2025

Severity of symptoms	Start	End	Difference
Slight	5.0	7.5	+2.5
Moderate	3.0	6.0	+3.0
Severe	0.0	3.0	+3.0

Severity of symptoms	Start	Reduction	No reduction
Slight	14	10	4
Moderate	26	19	7
Severe	0	9	1

Category: Publications

Intestinal Dysbiosis

What is dysbiosis?

How does dysbiosis develop?

What conditions or diseases depend on dysbiosis?

How will dysbiosis be inhibited?

What is probiotics?

What bacteria are there in the stomach and the intestine?

Fermentation and Putrefaction

What sort of diet promotes a healthy flora?

The Immune System and Lymphoid Tissue

Nitrogen Waste Products

What happens in the intestine biochemically and immunologically during probiotic therapy?

Detoxification and Retoxification

Conjugation and Deconjugation

Oestrogen

Endotoxins

Carcinogens and Insulin

Vitamins and Analogues

Certain Conditions When Probiotics Are of Importance

Disease-Specific Treatment

Weeks 1–4 (or even longer in severe cases)

Advanced Organ Support

Basic Detoxification and Drainage

Disease-Specific Treatment: Aletris-Heel

Weeks 1–2

Weeks 3–8: Advanced Organ Support

Weeks 9–20: Basic Detoxification and Drainage

Calcarea Carbonica

Calcarea Phosphorica

Calcarea Fluoricum

The following chart summarizes the characteristics of the three calcareas groups:

ANATOMICAL AND ORO-FACIAL KEYNOTES (including TMJ)

Bibliography

Recommended Reading

ESTIMATION OF CLINIC AND IMMUNOLOGIC EFFECTIVENESS OF THE USING OF PSORINOHEEL, LYMPHOMYOSOT AND MUCOSA COMPOSITUM S IN COMPLEX TREATMENT OF ATOPIC DERMATITIS IN CHILDREN

COMPLEX TREATMENT OF PATIENTS SUFFERING FROM DISCIRCULAR ENCEPHALOPATHY WITH USING ANTIHOMOTOXIC PREPARATIONS

THE EXPERIENCE OF USING ANTIHOMOTOXIC PREPARATIONS ANGIN-HEEL AND ENGYSTOL IN THE TREATMENT OF CHILDREN SUFFERING FROM ACUTE TONSILLITIS

POSSIBILITIES OF ANTIHOMOTOXIC PREPARATION THYREOIDEA COMPOSITUM IN THE TREATMENT OF CHILDREN SUFFERING FROM AUTOIMMUNE THYROIDITIS

USAGE OF ANTIHOMOTOXIC PREPARATIONS IN THE TREATMENT OF PATIENTS WITH CHRONIC HEPATITIS

EVALUATION OF THE EFFICIENCY OF COMPLEX ANTIHOMOTOXIC PREPARATIONS GRIPP-HEEL, ENGYSTOL AND EUPHORBIUM COMPOSITUM S IN PROPHYLAXIS AND TREATMENT OF GRIPPE AND ACUTE RESPIRATORY VIRAL INFECTIONS IN CHILDREN

A) Graph (reproduced qualitatively)

B) Assay‐Component Table

A) Graph

B) Assay-Component Table

A) Graph

B) Assay-Component Table

A) Graph

B) Assay-Component Table

A. Introduction

B. Injection of biotherapeutics

B.1. Injection of biotherapeutics is not a very strategic novelty

C. Biotherapeutics for local injections?

C.1. Subcutaneous injection

C.2. Acupuncture point injections

F. Is it always necessary to give injections?

Case:

Case:

G. Conclusion

What does neural therapy involve?

Neural (Greek)

Neuron

Neuron theory

HISTORICAL SUMMARY OF NEURAL THERAPY

Definition of focal disorder

Location of focal disorders

SEGMENT THERAPY

Head’s zones

HUNEKE’S INSTANTANEOUS PHENOMENON

THE TECHNIQUES OF NEURAL THERAPY

Instruments required

Wheal test

DEFINITIONS