Depresses heart, respiration and blood pressure, lowers temperature. Cyanosis and collapse. Increased susceptibility to cold. Destroys red blood corpuscles; pallor.

Head.–Enlarged sensation. Fainting. Moral depravity.

Eyes.–Pallor of optic discs, contracted visual field and shrinking retinal vessel; mydriasis.

Heart.–Weak, irregular, with blue mucous membranes, albuminuria, œdema of feet and ankles.

Relationship.–Compare: Antipyrin.

Dose.–Used as a sedative and antipyretic for various forms of headache and neuralgia in doses of one to three grains. For the homeopathic indications use the third potency.