Category: Biotherapeutic Index

DROPS

Composition:
Plantago major D1, Chamomilla D1, Schrophularia D1, Juniperus comm. gemmae D1, Chelidonium majus D1, Tabacum D6/9/12/30, Nicotinum D6/12/30, Coffea D6/12/30, Saccharum D6/9/12/30, Papaver 12CH, Caladium seg. D4, Nux vomica D6/9/12, Natrium muriaticum D9. Contains alcohol (30%).

Indications:
To overcome nicotine, alcohol, coffee, sugars and narcotic dependence.

Dosage:
30 drops at least 4 times a day.

Package sizes:
30 ml / 1.0 fl. oz. bottle with dropper. For oral use.

Product Link: https://urenus.com/en-us/products/metatox-02-nerve-calming-30ml-drops

DROPS

Composition:
Bone 10X/30X/200X Calcarea fluorica 12X/30X/200X Calcarea carbonica 12X/30X/200X Calcarea phosphorica 12X/30X/200X Calcitonin 6X L-isoleucine 3X L-leucine 3X L-lysine 3X L-methionine 3X L-phenylalanine 3X L-threonine 3X L-tryptophan 3X L-valine 3X Parathyroid gland 10X/30X/200X

Indications:
Adjuvant treatment of osteoporosis

Dosage:
20 drops twice a day for two months at least

Package sizes:
30 ml / 1.0 fl. oz. bottle with dropper. For oral use.

Pharmacological notes:
Stimulation of the fixation
of Ca in bones*
Stimulation of enzyme Modulation of parathyroid
mechanisms supervising function and relevant
metabolic processes involving parathormone synthesis
Ca salts and their fixation. and consequent reduction
of bone reabsorption**
Calcarea carb. 12/30/200X
Calcarea fluor. 12/30/200X
Calcitonin 6X*
Calcarea phosph. 12/30/200X
Parathyyroid gland10/30/200X**
MODULATION
REGULATION
OF OSTEOCLAST
OF BONE AND STIMULATION
METABOLISM OF OSTEOBLAST
ACTIVITY
TROPHIC
ACTION
ON BONES
Synergical action
involving trophic
Bone, 10/30/200X*
stimulation* and
Essential amino acids 3X**
optimization of amino acid
cell absorption**

Rational Structure according to GUNA-Method:
Stimulation of the fixation
of Ca in bones*
Stimulation of enzyme Modulation of parathyroid
mechanisms supervising function and relevant
metabolic processes involving parathormone synthesis
Ca salts and their fixation. and consequent reduction
of bone reabsorption**
Calcarea carb. 12/30/200X
Calcarea fluor. 12/30/200X
Calcitonin 6X*
Calcarea phosph. 12/30/200X
Parathyyroid gland10/30/200X**
MODULATION
REGULATION
OF OSTEOCLAST
OF BONE AND STIMULATION
METABOLISM OF OSTEOBLAST
ACTIVITY
TROPHIC
ACTION
ON BONES
Synergical action
involving trophic
Bone, 10/30/200X*
stimulation* and

Clinical notes & Combinations:
Osteobios + Guna-Fem: basic treatment of perimenopausal osteoporosis.
Osteobios + Guna-Cell + Guna-Matrix: remodeling of bone matrix.
Osteobios + Guna-Arthro: osteoporosis and osteochondrosis.

Product Link: https://urenus.com/en-us/products/osteobios-drops-30ml-drops

DROPS

Composition:
Glycyrrhiza glabra D1, Guaranà D1, Fucus vesiculosus TM, Stevia D1, Lycopodium D4, Gl. thyroidea 4CH, Badiaga D2, Cimicifuga D3, Iodum D12, Spongia tosta D4/12/15, Phytolacca D3, Hypophysis anterior 4CH, Hypophysis posterior 4CH, Hypothalamus 4CH. Contains alcohol (30%).

Indications:
To improve metabolic activity, reduce appetite, reduce hypoglycemia,
increase the general energy state of the organism.

Dosage:
30 drops at least 4 times a day.

Package sizes:
30 ml / 1.0 fl. oz. bottle with dropper. For oral use.

Product Link: https://urenus.com/en-us/products/metatox-03-metabolism-30ml-drops

INJECTION SOLUTION (STERILE VIALS)

Composition:
Active ingredient: Collagen of porcine origin (2 ml vial).
Ancillary substances: Arnica montana, Sodium chloride, Water for injection.

Indications:
• Improve the knee movement.
• Help muscle stretching.
• Soothe pain while moving legs and knee.

Dosage:
Therapeutic protocol: 1 treatment weekly for 10 consecutive
weeks.
Periarticular injection technique
(the site of application must be aseptic; insert the needle near
the sacroiliac joint at 2-4 mm depth)
For this purpose the use of the following materials and
accessories is recommended:
• Materials for aseptic skin preparation: single-use gloves, iodine solution, alcohol solution, sterile gauze pads, ethyl chloride spray for the skin.
• Needles: sterile 27 G. When a supportive treatment is needed for acute pain, MD-
• Syringes: 5 or 10 cc size, according to the volume of the KNEE can be associated with MD-NEURAL, MD-POLY and solution to inject. MD-MUSCLE (together with one or more than one of these). Intraarticular injection technique Moreover, when a supportive treatment is needed for the connective tissue matrix or when the physiological For this purpose the use of the following materials and aging process should be slowed down, MD-KNEE can be accessories is recommended: associated with MD-MATRIX and MD-TISSUE.
• Materials for aseptic skin preparation: single-use gloves, iodine solution, alcohol solution, sterile gauze pads, ethyl It may also be used as mechanical support while treating chloride spray for the skin. The application of a topical the following diseases: anaesthetic on the skin area to be treated is recommended. • Knee arthrosis (in association with MD-POLY).
• Needles: sterile 22 G. • Patello-femoral arthrosis.
• Syringes: 2 cc size, according to the volume of the solution • Knee localization of rheumatoid arthritis or of other to inject. autoimmune diseases (in association with MD-POLY).
• Knee acute and chronic arthrosynovitis secondary to arthrosis or to rheumatoid arthritis (in association with Knee – Intraarticular injection technique (internal side) MD-POLY). The patient should lay supine with the knee comfortably extended. A 22 G • Post-traumatic or post-surgery acute and chronic needle is inserted in a direction parallel to the plane of the posterior surface of arthrosynovitis. the patella in a medial and lateral position.
• Traumatic lesions of cruciate or collateral ligaments of the knee.

Package sizes:
Box of 10 sterile vials (2 ml each).

Clinical notes & Combinations:
• Meniscal lesions (in association with MD-MUSCLE).
• Knee joint preparation to meniscectomy (in association MD-KNEE may be used as a single treatment or mixed with with MD-MUSCLE). other medical devices of the same range, in order to make a • Maintenance therapy after knee surgery (in association customised treatment according to clinical evolution. with MD-MUSCLE and MD-NEURAL).

Product Link: https://urenus.com/en-us/products/md-knee-pack-of-10-ampoules-of-2ml

INJECTION SOLUTION (STERILE VIALS)

Composition:
Active ingredient: Collagen of porcine origin (2 ml vial).
Ancillary substances: Hamamelis virginiana, Sodium chloride, Water for injection.

Indications:
• Help lumbar movement
• Help muscle stretching of the lumbosacral area of the spine.
• Help to support the lumbar muscle tissue.
• Soothe local pain, pain at rest or caused by movement and bad posture.

Dosage:
Therapeutic protocol:
• Acute pathologies: 2 treatments weekly for the first 2 weeks; 1 treatment until improvement of symptoms (average 8-10 sessions).
• Chronic pathologies: go on with 1 treatment weekly for one month until improvement of symptoms, then with 1 treatment monthly or – according to individual needs – It may also be used as mechanical support while treating every 45-50 days. the following diseases: Periarticular injection technique • Lumbar pain secondary to cartilage degenerative lumbar (The site of application must be aseptic. Insert the needle near spine disorders (lumbar and lumbar-sacral arthrosis). the lumbar and lumbosacral joints at 3-4 mm depth) • Lumbar vertebral osteophytosis.
• Low-back pain secondary to musculo-tendinous trigger For this purpose the use of the following materials and points (in association with MD-MUSCLE). accessories is recommended:
• Postural low-back aches (in association with MD-NEURAL
• Materials for aseptic skin preparation: single-use gloves, and MD-MUSCLE). iodine solution, alcohol solution, sterile gauze pads, ethyl
• Lumbar and lumbar-sacral mechanical imbalance. chloride spray for the skin.
• Lumbar and lumbar-sacral spinal ligament syndrome.
• Needles: sterile 27 G.
• Sacro-iliac syndrome.
• Syringes: 5 or 10 cc size, according to the volume of the
• Spinal lumbar and lumbar-sacral nerve root pain (in solution to inject. association with MD-NEURAL and MD-ISCHIAL).

Package sizes:
Box of 10 sterile vials (2 ml each).

Clinical notes & Combinations:
MD-LUMBAR may be used as a single treatment or mixed
with other medical devices of the same range, in order to
make a customised treatment according to clinical evolution.
When a supportive treatment is needed for acute pain, MDLUMBAR can be associated with MD-NEURAL, MD-POLY and
MD-MUSCLE (together with one or more than one of these).
Moreover, when a supportive treatment is needed for the
connective tissue matrix or when the physiological aging
process should be slowed down, MD-LUMBAR can be
associated with MD-MATRIX and MD-TISSUE.

Product Link: https://urenus.com/en-us/products/md-lumbar-pack-of-10-ampoules-of-2ml

INJECTION SOLUTION (STERILE VIALS)

Composition:
Active ingredient: Collagen of porcine origin (2 ml vial).
Ancillary substances: Citric acid, Nicotinamide, Sodium chloride, Water for injection.

Indications:
• Help movement by limiting a physiological degeneration of joints and tissues as well as by counterbalancing any damage caused by: ageing, bad posture, concomitant chronic diseases, blows and injuries. pollutants.
• Help movement, by strengthening the supportive tissue of the joints, and of the skin and its subcutaneous tissue. Its main therapeutic functions include: a barrier effect, a lubricating action, mechanical support while administering other pharmacological treatments.
• Due to its special function, MD-MATRIX is also intended for firming the subcutaneous and microvascular connective tissue layer of localized adiposities and cellulite in the connective tissue, especially those at the root of the thighs and in the inner area of the knee, in particular:

Dosage:
and for firming the subcutaneous connective tissue layer,
MD-MATRIX should preferably be associated with MDTherapeutic protocol: 2 treatments weekly for the first 2 weeks, TISSUE (e.g. MD-MATRIX 2 vials, MD-TISSUE 1 vial /
1 treatment weekly until improvement of symptoms (average treatment).
8-10 sessions). It is possible to go on with 1 treatment every • It may also be used in patients who need a collagen
other week for 10 weeks at most. For chronic pathologies: supplementation or a topical anti-ageing treatment.
go on with 1 treatment weekly for 1 month until improvement
of symptoms, then 1 treatment monthly.
Intradermal and subcutaneous injection technique (the site of
application must be aseptic; insert the needle at 1-3 mm depth
and microinject 0.2-0.3 ml into the affected tissue.)
Periarticular injection technique (the site of application must
be aseptic; insert the needle near the joint at different depths.)
For this purpose the use of the following materials and
accessories is recommended:
• Materials for aseptic skin preparation: single-use gloves, iodine solution, alcohol solution, sterile gauze pads, ethyl chloride spray for the skin.
• Needles: sterile 27 G, 4 mm.
• Syringes: 5 or 10 cc size, according to the volume of the solution to inject.

Package sizes:
Box of 10 sterile vials (2 ml each).

Clinical notes & Combinations:
• Strengthen the extra-cellular matrix tissues where the collagen is applied. • MD-MATRIX may be used as a single treatment or mixed with other medical devices of the same range, in order
• Act as a defensive barrier against free radicals. to make a customised treatment according to clinical evolution.
• Concerning its use for the treatment of localized adiposity,

Product Link: https://urenus.com/en-us/products/md-matrix-pack-of-10-ampoules-of-2ml

INJECTION SOLUTION (STERILE VIALS)

Composition:
Active ingredient: Collagen of porcine origin (2 ml vial).
Ancillary substances: Hypericum perforatum, Sodium chloride, Water for injection.

Indications:
• Help muscle stretching and function.
• Help to support the muscle tissue in bad posture disorders.
• Improve joint movement.
• Soothe local pain, or pain caused by movement and bad posture.

Dosage:
Therapeutic protocol: 1-2 treatments weekly for 10
consecutive weeks.
Intramuscular injection technique
(the site of application must be aseptic; insert the needle into
the muscle to be treated at 2-4 mm depth)
It may also be used as mechanical support while treating
For this purpose the use of the following materials and the following diseases:
accessories is recommended:
• Pain management: acute, subacute, and chronic.
• Materials for aseptic skin preparation: single-use gloves,
• Referred somatic pain area management (in association iodine solution, alcohol solution, sterile gauze pads, ethyl with MD-NEURAL) chloride spray for the skin.
• Trigger points management (in association with MD-
• Needles: sterile 27 G. NEURAL)
• Syringes: 5 or 10 cc size, according to the volume of the
• Fibromyalgia syndrome (in association with MD-NEURAL) solution to inject.
• Dermatomyositis. Intramuscular injection technique Administration may vary according to individual needs. For this purpose the use of the following materials and accessories is recommended:
• Materials for aseptic skin preparation: single-use gloves, iodine solution, alcohol solution, sterile gauze pads, ethyl chloride spray for the skin. The application of a topical anaesthetic to the skin is recommended.
• Needles: sterile 22 G.
• Syringes: 2 cc size, according to the volume of the solution to inject.

Package sizes:
Box of 10 sterile vials (2 ml each).

Clinical notes & Combinations:
MD-MUSCLE may be used as a single treatment or mixed
with other medical devices of the same range, in order to
make a customised treatment according to clinical evolution.
When a supportive treatment is needed for the connective
tissue matrix or when an antiaging action is necessary,
MD-MUSCLE can be associated with MD-MATRIX and MDTISSUE.

Product Link: https://urenus.com/en-us/products/md-muscle-pack-of-10-ampoules-of-2ml

INJECTION SOLUTION (STERILE VIALS)

Composition:
Active ingredient: Collagen of porcine origin (2 ml vial).
Ancillary substances: Silicea, Sodium chloride, Water for injection.

Indications:
• Improve the movement of the cervical tract of the spine.
• Help cervical muscle stretching.
• Help to support cervical muscle tissue.
• Help to support cervical muscle tissue in bad posture disorders.
• Soothe pain in cervical column movements.

Dosage:
Therapeutic protocol: 1-2 treatments weekly for 10
consecutive weeks.
Periarticular injection technique (the site of application must be
aseptic; insert the needle at 2-4 mm depth).
For this purpose the use of the following materials and
accessories is recommended:
• Materials for aseptic skin preparation: single-use gloves, • Simple neck pain (in association with MD-NEURAL and iodine solution, alcohol solution, sterile gauze pads, ethyl MD-MUSCLE) chloride spray for the skin. • Whiplash (in association with MD-NEURAL and MD-
• Needles: sterile 27 G. MUSCLE)
• Syringes: 5 or 10 cc size, according to the volume of the • Postural neck ache (in association with MD-NEURAL and solution to inject. MD-MUSCLE)
• Mechanical imbalance (facet joint syndrome) (in association with MD-NEURAL)

Package sizes:
Box of 10 sterile vials (2 ml each).

Clinical notes & Combinations:
• Cervical spinal ligament syndrome (in association with MD-NEURAL) MD-NECK may be used as a single treatment or mixed with
• Cervical spinal nerve root pain (in association with MDother medical devices of the same range, in order to make NEURAL). a customised treatment according to clinical evolution. Administration may vary according to individual needs. When a supportive treatment is needed for acute pain, MDNECK can be associated with MD-NEURAL, MD-POLY and MD-MUSCLE (together with one or more than one of these). Moreover, when a supportive treatment is needed for the connective tissue matrix or when the physiological aging process should be slowed down, MD-NECK can be associated with MD-MATRIX and MD-TISSUE. It may also be used as mechanical support while treating the following diseases:
• Neck pain due to cartilage degenerative cervical spine disorders (cervical osteoarthritis, in association with MDPOLY)
• Neck pain due to cervical muscular trigger points (in association with MD-MUSCLE)
• Stiff neck syndrome (in association with MD-NEURAL)

Product Link: https://urenus.com/en-us/products/md-neck-pack-of-10-ampoules-of-2ml

INJECTION SOLUTION (STERILE VIALS)

Composition:
Active ingredient: Collagen of porcine origin (2 ml vial).
Ancillary substances: Citrullus colocynthis, Sodium chloride, Water for injection.

Indications:
• MD-NEURAL is a medical device designed to help joint movement, specifically in bad posture disorders. Its main therapeutic functions include: barrier effect, lubricating action, mechanical support while administering other pharmacological treatments.

Dosage:
Therapeutic protocol: 1-2 treatments weekly for 10
consecutive weeks.
Periarticular injection technique (the site of application must be
aseptic; insert the needle at 2-4 mm depth).
For this purpose the use of the following materials and
It may also be used as mechanical support while treating
accessories is recommended:
the following diseases:
• Materials for aseptic skin preparation: single-use gloves, iodine solution, alcohol solution, sterile gauze pads, ethyl • Brachial pain (in association with MD-NECK) chloride spray for the skin. • Brachial nerve pain due to cervical entrapment (in
• Needles: sterile 27 G. association with MD-NECK)
• Syringes: 5 or 10 cc size, according to the volume of the • Persistent intercostal neuralgia (in association with MDsolution to inject. THORACIC)
• Postherpetic neuralgia (in association with MDIntraarticular injection technique THORACIC or MD-LUMBAR) For this purpose the use of the following materials and • Atypical facial neuritis (in association with MD-NECK) accessories is recommended: • Trigeminal neuralgia (in association with MD-NECK)
• Materials for aseptic skin preparation: single-use gloves, • Temporomandibular joint pain (in association with MDiodine solution, alcohol solution, sterile gauze pads, NECK) ethyl chloride spray for skin.The application of a topical • Cervical, thoracic, lumbar and sacrolumbar nerve root anaesthetic on the skin area to be treated is recommended. pain (respectively in association with MD-NECK, MD-
• Needles: sterile 22 G. THORACIC, MD-LUMBAR and MD-ISCHIAL).
• Syringes: 2 cc size, according to the volume of the solution to inject.

Package sizes:
Box of 10 sterile vials (2 ml each).

Clinical notes & Combinations:
MD-NEURAL may be used as a single treatment or mixed
with other medical devices of the same range, in order to
make a customised treatment according to clinical evolution.
When a supportive treatment is needed for the connective
tissue matrix or when an antiaging action is necessary,
MD-NEURAL can be associated with MD-MATRIX and MDTISSUE.

Product Link: https://urenus.com/en-us/products/md-neural-pack-of-10-ampoules-of-2ml

INJECTION SOLUTION (STERILE VIALS)

Composition:
Active ingredient: Collagen of porcine origin (2 ml vial).
Ancillary substances: Drosera rotundifolia, Sodium chloride, Water for injection.

Indications:
• Improve movement of the joints.
• Help muscle stretching.
• Help to support the muscle tissue in bad posture disorders.
• Soothe local pain, or pain caused by movement and bad posture.

Dosage:
Therapeutic protocol:1-2 treatments weekly for 10
consecutive weeks.
Periarticular injection technique (the site of application must be
aseptic; insert the needle at 3-6 mm depth)
For this purpose the use of the following materials and
accessories is recommended:
• Materials for aseptic skin preparation: single-use gloves, following diseases: iodine solution, alcohol solution, sterile gauze pads, ethyl
• Small joints rheumatoid arthritis of hand and foot (in chloride spray for the skin. association with MD-SMALL JOINTS)
• Needles: sterile 27 G.
• Non-specific diffuse pain (in association with MD-NECK
• Syringes: 5 or 10 cc size, according to the volume of the and MD-NEURAL) solution to inject.
• Costo-sternal syndrome (in association with MD-NEURAL) Intraarticular injection technique • Chronic polyarthritis due to auto-immune diseases (e.g. Lupus erithematosus sistemicus) (in association with MDFor this purpose the use of the following materials and NEURAL when nerve pain is dominant; in association accessories is recommended: with MD-MUSCLE when muscle pain is dominant)
• Materials for aseptic skin preparation: single-use gloves,
• Breakbone fever (when nerve pain is dominant in iodine solution, alcohol solution, sterile gauze pads, association with MD-NEURAL; when muscle pain is ethyl chloride spray for skin.The application of a topical dominant in association with MD-MUSCLE) anaesthetic on the skin area to be treated is recommended.
• Joint pain due to viral or protozoic disease (in association
• Needles: sterile 22 G. with another Guna medical device containing the same
• Syringes: 5 or 10 cc size, according to the volume of the type of collagen contained in the joint to be treated) solution to inject.
• Joint pain due to cancer (chronic leukaemia, multiple myeloma) (in association with another Guna medical device containing the same type of collagen contained in

Package sizes:
Box of 10 sterile vials (2 ml each).

Clinical notes & Combinations:
the joint to be treated).
MD-POLY may be used as a single treatment or mixed with
other medical devices of the same range, in order to make a
customised treatment according to clinical evolution.
When a supportive treatment is needed for the connective
tissue matrix or when an antiaging action is necessary, MDPOLY can be used together with MD-MATRIX and MD-TISSUE.
It may also be used as mechanical support while treating the

Product Link: https://urenus.com/en-us/products/md-poly-pack-of-10-ampoules-of-2ml