PROFEM PLUS

SACHETS

Composition:
, such as isoflavones (79 mg per sachet) and the specific nutrients that favour a balanced gut flora.

Indications:
for hormone replacement
P-21020), Lactobacillus rhamnosus LR06 (DSM
therapy or who prefer to use natural replacement
21981), Lactobacillus salivarius LS03 (DSM 22776);
options.Thanks to the presence of Lactobacillus
Sweetener: sucralose; Clover (Trifolium pratense L.)
rhamnosus LR06 and Lactobacillus plantarum
leaves and flowers -min. 8% isoflavones; Melatonin.
LP02, able to produce coliform bacteria-limiting
Anti-caking agent:silicon dioxide.
active substances (bacteriocins), it is particularly
recommended even in subjects with frequent

Dosage:
The recommended dose is one sachet a day, preferably between meals. Dissolve the content of the sachet in half a glass of water at room temperature, stir well and drink immediately.

Package sizes:
recurrent genito-urinary tract infections, caused by Escherichia coli.

Pharmacological notes:
Secreting Gland / Source: , titrated and and viable, with five times the colonising ability
Profem
The synergetic and complementary action
of Profem is fortified by the presence of 6
“microencapsulated gastro-protected” lactic
absorbable and highly bioavailable. In addition
acid bacteria with a probiotic action. The use
to targeting neurovegetative symptoms, it also has
of this certified technique improves the survival
a cardiovascular and bone protection action.
capacity of all the probiotic bacteria during their 2nd nucleus: green tea and melatonin
gastroduodenal transit, to allow all the strains to The presence of green tea in Profem guarantees
reach the intestine alive and healthy. Here, the a significant anti-ageing action, secondary to
probiotic bacteria activate the isoflavones, making its antioxidant activity. Green tea also helps to
them more bioavailable. maintain stable body weight.
Melatonin is known for its ability to rebalance the
circadian rhythms and to maintain neurovegetative
How it works
balance (particularly during the menopause).
Profem has 4 nuclei with synergetic actions: 3rd nucleus: 6 gastro-protected strains of probiotic
1st nucleus: the isoflavones pool bacteria
The core of Profem is the nucleus of isoflavones The gastro-protected microencapsulated probiotic
(79 mg per sachet), the most important category of bacteria reach the various parts of the intestine alive
natural phytoestrogens of plant origin, titrated and and viable, with five times the colonising ability
standardised. of non-microencapsulated probiotic bacteria(3),
Profem contains a unique pool of isoflavones in for the greatest possible availability of the
special proportional combination, which exerts an isoflavones. The health of the gut flora is essential
effective control action over even intense vasomotor for the optimum absorption and biological activity
symptoms (nocturnal perspiration, hot flushes, mood of the isoflavones, as Daidzein and Genistein
swings, etc.) that occur during the menopause. (Formononetin is demethylated to Daidzein by
The ingredients in the 1st nucleus are: Lactobacilli glucosidase), are transformed into the
Soy (Glycine max Merr.): plant with a very high active metabolite Equol.
content of isoflavones (especially Genistein and 4th nucleus: short-chain fructo-oligosaccharides
Daidzein) with a hormonal-like action. (scFOS) with a specific prebiotic action
Pueraria lobata Merr. (Kudzu): contains Daidzein, Obtained from sugar beet, they promote and
Formononetin and Puerarin, which make it the ideal selectively stimulate the development of the probiotic
solution for controlling menopausal symptoms, for its bacteria – Lactobacilli and Bifidobacteria – present
action on the microcirculation and on physiological in the gut microbiota: ScFOS play a positive role in
blood pressure. the metabolism of carbohydrates and lipids, they
Red clover (Trifolium pratense L.): legouminous plant improve intestinal mucosal function and favour the
with a very high content of isoflavones, readily absorption of calcium and magnesium.
(3) Del Piano M. et Al. – Evaluation of the intestinal colonisation by microencapsulated probiotic bacteria in comparison with the
same uncoated strains. J. Clin Gastroenterol. 2010 Sept; 44 Suppl. 1:S42-6. Double-blind study
Who is Profem recommended for micro-encapsulated probiotics: Bifidobacterium lactis
BS01 (LMG P-21384), Lactobacillus acidophilus
Pre-menopausal, peri-menopausal and
LA02 (DSM 21717), Lactobacillus paracasei LPC00
menopausal women, who do not wish to use or
(LMG P-21380), Lactobacillus plantarum LP02 (LMG
have contraindications for hormone replacement
P-21020), Lactobacillus rhamnosus LR06 (DSM
therapy or who prefer to use natural replacement
21981), Lactobacillus salivarius LS03 (DSM 22776);
options.Thanks to the presence of Lactobacillus
Sweetener: sucralose; Clover (Trifolium pratense L.)
rhamnosus LR06 and Lactobacillus plantarum
leaves and flowers -min. 8% isoflavones; Melatonin.
LP02, able to produce coliform bacteria-limiting
Anti-caking agent:silicon dioxide.
active substances (bacteriocins), it is particularly
recommended even in subjects with frequent

Clinical notes & Combinations:
Profem + Colostrononi: menopausal symptoms characterised by strong bowel dysfunction.
Profem + Vit Formula: menopausal symptoms characterized by vitamin and/ or mineral deficiency.
Profem + Gunamino Formula: menopausal symptoms accompanied by weight gain and loss of muscle
tone.
Profem + Gunabasic: adjuvant treatment of osteoporosis.

Warnings and Precautions:
and storage
The ADVANTAGES of Profem
Store the product in a cool and dry place, away from direct light, and at
• It provides isoflavones of natural origin and a temperature not exceeding 25°C. A minimum total probiotic bacteria selected nutrients, for female psycho-physical content of 2 billion is guaranteed up to the expiry date indicated on wellness. the label, provided the product is stored in its original packaging at a temperature of no more than 25°C.The expiration date refers to the
• The total isoflavone content is 79 mg for each product correctly stored in its original and undamaged packaging. Do daily dose (1 sachet) not use during pregnancy. Do not exceed the recommended daily dose.
• Gluten, lactose and glucose-free Keep out of the reach of young children. Food supplements should not be considered as a substitute for a varied diet and a healthy lifestyle. It
• Its plant ingredients are not obtained from contains soy derivatives. Excessive consumption may produce laxative genetically-modified organisms (GMO-free) effects.
• Presence of melatonin, which rebalances the neuroendocrine circuits and helps to fall asleep Nutrition facts quickly. Directions The recommended dose is one sachet a day, preferably between meals. Dissolve the content of the sachet in half a glass of water at room temperature, stir well and drink immediately. Ingredients Sweetener: sorbitol; Fructo-oligosaccharides (FOS); Fructose; Soy (Glycine max L.) seeds – min. 10% isoflavones; Baked apple aroma; Green tea (Camellia sinensis L. Kuntze) leaves – min. 50% polyphenols; Pueraria lobata (Pueraria lobata Willd. Ohwi.) root
• min. 40% isoflavones; Acidity regulator: citric acid; Most common combinations Profem + Colostrononi: menopausal symptoms characterised by strong bowel dysfunction. Profem + Vit Formula: menopausal symptoms characterized by vitamin and/ or mineral deficiency. Profem + Gunamino Formula: menopausal symptoms accompanied by weight gain and loss of muscle tone. Profem + Gunabasic: adjuvant treatment of osteoporosis.

Product Link: https://urenus.com/en-us/products/profem-plus