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Zeel®
Compositions:
Tablets: 1 tablet containing: Cartilago suis D4 0.3 mg, Funiculus umbilicalis suis D4 0.3 mg, Embryo totalis suis D4 0.3 mg, Placenta totalis suis D4 0.3 mg, Rhus toxicodendron D2 0.54 mg, Arnica montana D1 0.6 mg, Solanum dulcamara D2 0.15 mg, Symphytum officinale D8 0.15 mg, Sanguinaria canadensis D3 0.45 mg, Sulfur D6 0.54 mg, Nadidum D6 0.03 mg, Coenzyme A D6 0.03 mg, Natrium diethyloxalaceticum D6 0.03 mg, Acidum DL-alpha liponicum D6 0.03 mg, Acidum silicicum D6 3 mg.
Injection solution: 1 ampoule of 2.0 ml (≈ 2.0 g) contains: Cartilago suis D6 2 mg, Funiculus umbilicalis suis D6 2 mg, Embryo totalis suis D6 2 mg, Placenta totalis suis D6 2 mg, Solanum dulcamara D3 10 mg, Symphytum officinale D6 10 mg, Nadidum D8 2 mg, Coenzyme A D8 2 mg, Sanguinaria canadensis D4 3 mg, Natrium diethyloxalaceticum D8 2 mg, Acidum DL-alpha liponicum D8 2 mg, Rhus toxicodendron D2 10 mg, Arnica montana D4 200 mg, Sulfur D6 3.6 mg.
Ointment: 100 g containing: Cartilago suis D2, Funiculus umbilicalis suis D2, Embryo suis D2, Placenta suis D2 0.001 g each; Rhus toxicodendron D2 0.270 g; Arnica montana D2 0.3 g; Solanum dulcamara D2 0.075 g; Symphytum officinale D8 0.75 g; Sanguinaria canadensis D2 0.225 g; Sulfur D6 0.27 g; Nadidum D6, Coenzyme A D6, Acidum DL-alpha liponicum D6, Natrium diethyloxalaceticum D6 0.01 g each; Acidum silicicum D6 1.0 g.
Ointment base: Hydrophilic ointment (DAB 10) containing: emulsifying cetostearyl alcohol (type A), ethanol, purified water, liquid paraffin, white soft paraffin, preserved with 12.8 vol.-% alcohol.
Indications:
Arthrosis/osteoarthritis, in particular knee arthrosis, polyarthrosis, spondylarthrosis, rotator cuff syndrome. Rheumatic joint diseases.
Contraindications:
Known allergy (hypersensitivity) to one or more of the ingredients. Do not use during pregnancy and lactation.
Side effects:
Tablets, injection solution: Allergic (hypersensitivity) skin reactions may occur in very rare cases (i.e. affects less than 1 in 10,000 users).
Interactions with other medication:
None known.
Dosage:
Tablets – Standard dosage: Adults (and children 12 yrs. and older): 1 tablet to be dissolved in the mouth 3x daily. Acute or initial dosage: 1 tablet every ½ to 1 hr., up to 12x daily, then continue with standard dosage.
Injection solution – Standard dosage: Adults and children 12 yrs. and older: 1 ampoule 1 to 3x weekly. May be administered by s.c., i.d., i.m., i.a. or i.v. route. Acute or initial dosage: 1 ampoule daily, then continue with standard dosage.
Ointment – Standard dosage: Adults (and children 12 yrs. and older): Apply 2 to 4x daily. For external use only. Apply a thin layer over the affected area.
Package sizes:
- Tablets: Packs containing 50 and 250 tablets. (9757)
- Injection solution: Packs containing 10 and 100 ampoules of 2.0 ml each. (8705)
- Ointment: Tubes containing 50 and 100 g of ointment. (9588)
Clinical notes:
Zeel may protect against aspects of cartilage damage. The chondrocyte, which is the “control center” of the cartilage, regulates the oscillatory cycle of tissue destruction and regeneration, influenced by IL-6, IL-1, and TNF-α. These cytokines affect matrix metalloproteinases and synthesis of other substances. The regenerative cycle is supported by transforming growth factor-β and plant-based ingredients in Zeel.
Zeel’s ingredients such as sulfur and cartilage-based tissue materials (e.g., Cartilago suis and Funiculus umbilicalis suis) may support connective tissue regeneration and modulate inflammation.
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